STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KLHL6Kelch like family member 6. (621 aa)    
Predicted Functional Partners:
PTPN14
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily.
      
 0.884
RC3H2
Ring finger and CCCH-type domains 2.
   
 
 0.652
CUL3
Cullin 3; Belongs to the cullin family.
    
 0.642
EPHB4
EPH receptor B4.
    
 0.621
ICOS
Inducible T cell costimulator.
   
  
 0.621
BBS9
Bardet-Biedl syndrome 9.
    
 0.568
TIE1
Tyrosine kinase with immunoglobulin like and EGF like domains 1.
   
  
 0.567
BBS1
BBS1 domain-containing protein.
    
 0.566
BBS4
Bardet-Biedl syndrome 4.
    
 0.555
BBS7
Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.
   
 0.553
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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