STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CRYBB1Crystallin beta B1; Belongs to the beta/gamma-crystallin family. (252 aa)    
Predicted Functional Partners:
GJA3
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
   
  
 0.838
GJA8
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
   
  
 0.824
ITSN2
Intersectin 2.
   
 0.819
TMEM114
Transmembrane protein 114.
    
 
 0.801
CRYBA1
Crystallin beta A1; Belongs to the beta/gamma-crystallin family.
  
 
0.794
WFS1
Wolframin ER transmembrane glycoprotein.
      
 0.762
LOC100973228
SHSP domain-containing protein; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.
   
  
 0.749
BFSP2
Beaded filament structural protein 2; Belongs to the intermediate filament family.
    
 0.749
TRPM3
Transient receptor potential cation channel subfamily M member 3.
      
 0.726
FYCO1
FYVE and coiled-coil domain containing 1.
    
 0.725
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.