Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TRIM42Tripartite motif containing 42. (723 aa)    
Predicted Functional Partners:
CCIN
Calicin.
   
   0.818
CREB5
Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription.
    
   0.641
TRIM69
Tripartite motif containing 69.
   
 
 0.604
TRIM23
Tripartite motif containing 23.
    
 0.592
FSD2
Fibronectin type III and SPRY domain containing 2.
      
 0.555
ENSPPAP00000000414
Uncharacterized protein.
    
 
 0.519
IGBP1
Immunoglobulin binding protein 1.
    
 
 0.519
FAM166A
Family with sequence similarity 166 member A.
   
    0.501
EFHC2
EF-hand domain containing 2.
   
    0.499
YWHAQ
14_3_3 domain-containing protein; Belongs to the 14-3-3 family.
    
   0.499
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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