Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GBP4Guanylate binding protein 4. (640 aa)    
Predicted Functional Partners:
ENSPPAP00000037876
GB1/RHD3-type G domain-containing protein.
   
 0.888
GBP5
Guanylate binding protein 5.
   
  0.883
GBP2
Guanylate binding protein 2.
   
 0.707
GBP3
Guanylate binding protein 3.
   
 0.646
STAT1
Signal transducer and activator of transcription.
   
 0.555
IRF1
Interferon regulatory factor.
   
 0.554
FURIN
Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family.
   
 
 0.542
PARP14
Poly [ADP-ribose] polymerase.
   
 
 0.519
CASP1
Caspase 1; Belongs to the peptidase C14A family.
   
 
 0.516
LGALS8
Galectin.
   
 
 0.496
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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