Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AGFG1ArfGAP with FG repeats 1. (528 aa)    
Predicted Functional Partners:
VAMP7
Vesicle associated membrane protein 7; Belongs to the synaptobrevin family.
    
 0.905
EPS15
Epidermal growth factor receptor pathway substrate 15.
    
 0.879
EPS15L1
Epidermal growth factor receptor pathway substrate 15 like 1.
    
 0.826
RAB1A
RAB1A, member RAS oncogene family.
   
  
 0.747
ITSN2
Intersectin 2.
    
 0.713
TMPRSS12
Transmembrane serine protease 12; Belongs to the peptidase S1 family.
      
 0.686
RAB11A
RAB11A, member RAS oncogene family.
      
 0.667
ITSN1
Intersectin 1.
    
 0.646
RAB5A
RAB5A, member RAS oncogene family.
      
 0.638
RAB2A
RAB2A, member RAS oncogene family.
      
 0.631
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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