Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MAN2B2Alpha-mannosidase. (1098 aa)    
Predicted Functional Partners:
MAN2C1
Mannosidase alpha class 2C member 1.
     
 0.938
MAN2B1
Alpha-mannosidase.
     
0.932
MANBA
Mannosidase beta.
   
 
 0.904
FLT3LG
Uncharacterized protein.
   
  
 0.832
MYADM
Myeloid associated differentiation marker.
      
 0.803
DDX25
DEAD-box helicase 25.
      
 0.777
ENOSF1
Enolase superfamily member 1.
      
 0.773
ENPP2
Ectonucleotide pyrophosphatase/phosphodiesterase 2.
      
 0.729
GSTM4
Uncharacterized protein; Belongs to the GST superfamily.
      
 0.715
ZPBP2
Zona pellucida binding protein 2.
      
 0.714
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
Server load: low (18%) [HD]