STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NPPBNatriuretic peptide B. (134 aa)    
Predicted Functional Partners:
NPR3
Natriuretic peptide receptor 3.
    
 0.993
NPR1
Guanylate cyclase.
    
 0.992
NPPA
Natriuretic peptide A.
   
 
 0.962
NPR2
Guanylate cyclase.
    
 0.898
IDE
Insulin degrading enzyme; Belongs to the peptidase M16 family.
    
 
 0.865
TNNI3
Troponin I3, cardiac type.
   
  
 0.739
CORIN
Corin, serine peptidase.
     
 0.720
MYH7
Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
  
 0.693
NPPC
Natriuretic peptide C.
      
 0.690
CRP
Uncharacterized protein.
      
 0.684
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.