STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TRIM55Tripartite motif containing 55. (548 aa)    
Predicted Functional Partners:
TICAM2
TIR domain-containing adaptor molecule 2.
    
 
 0.879
TTN
Uncharacterized protein.
   
 
 0.730
ENSPPAP00000028441
Uncharacterized protein.
   
 
 0.730
BBOX1
Gamma-butyrobetaine hydroxylase 1.
      
 0.673
NBR1
NBR1 autophagy cargo receptor.
    
 0.608
SQSTM1
Sequestosome 1.
    
 0.608
PNRC1
Proline rich nuclear receptor coactivator 1.
      
 0.555
TRIM52
Tripartite motif-containing protein 52.
      
 0.549
TRIM5
Tripartite motif-containing protein 5; Capsid-specific restriction factor that prevents infection from non-host-adapted retroviruses. Blocks viral replication early in the life cycle, after viral entry but before reverse transcription. In addition to acting as a capsid-specific restriction factor, also acts as a pattern recognition receptor that activates innate immune signaling in response to the retroviral capsid lattice. Binding to the viral capsid triggers its E3 ubiquitin ligase activity, and in concert with the heterodimeric ubiquitin conjugating enzyme complex UBE2V1- UBE2N (als [...]
    
 
 0.463
TRIM63
Tripartite motif containing 63.
   
  
0.437
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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