STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCRIBScribble planar cell polarity protein. (1656 aa)    
Predicted Functional Partners:
VANGL2
Vang-like protein.
    
 0.975
ARHGEF7
Rho guanine nucleotide exchange factor 7.
    
 0.967
UBE3A
Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.
    
 0.950
LLGL1
LLGL scribble cell polarity complex component 1.
    
 0.945
LLGL2
LLGL scribble cell polarity complex component 2.
    
 0.943
DLG4
Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.
   
0.918
DLG1
Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family.
   
0.917
DLG3
Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family.
   
0.912
DLG5
Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family.
    
0.891
PHLPP1
Uncharacterized protein.
    
0.879
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.