STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)    
Predicted Functional Partners:
HEY2
Hes related family bHLH transcription factor with YRPW motif 2.
    
0.988
HEYL
Hes related family bHLH transcription factor with YRPW motif like.
  
  
0.950
SKP1
S-phase kinase associated protein 1; Belongs to the SKP1 family.
    
 
 0.837
HES1
Hes family bHLH transcription factor 1.
    
0.808
NOTCH1
Notch receptor 1.
    
 0.793
CLK4
CDC like kinase 4; Belongs to the protein kinase superfamily.
      
 0.760
NOTCH4
Notch receptor 4.
   
 0.743
RBPJ
Recombination signal binding protein for immunoglobulin kappa J region.
    
 0.707
JAG1
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
    
 0.705
RUNX2
RUNX family transcription factor 2.
    
 0.700
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.