STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC100979625Uncharacterized protein. (545 aa)    
Predicted Functional Partners:
CDC42
Uncharacterized protein.
    
 
 0.925
LOC100993131
Cell division control protein 42 homolog.
    
 
 0.925
ENSPPAP00000028117
Uncharacterized protein.
 
      0.899
GRB2
Growth factor receptor bound protein 2.
    
 
 0.823
CLTC
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.
    
 
 0.784
EGFR
Receptor protein-tyrosine kinase.
   
 
 0.731
NEDD4L
NEDD4 like E3 ubiquitin protein ligase.
    
 
 0.645
TNK1
Tyrosine kinase non receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family.
 
     
0.640
NCK1
Cytoplasmic protein.
    
 
 0.590
HSP90AA1
HATPase_c domain-containing protein.
    
 
 0.590
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.