STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AUNIPAurora kinase A and ninein interacting protein. (371 aa)    
Predicted Functional Partners:
DTL
Denticleless E3 ubiquitin protein ligase homolog.
   
  
 0.606
ERCC6L
ERCC excision repair 6 like, spindle assembly checkpoint helicase.
   
  
 0.539
TINF2
TERF1 interacting nuclear factor 2.
  
     0.498
LAX1
Lymphocyte transmembrane adaptor 1.
  
     0.485
MCM10
Minichromosome maintenance 10 replication initiation factor.
   
  
 0.484
TCOF1
Treacle ribosome biogenesis factor 1.
  
     0.448
IL18BP
Interleukin 18 binding protein.
  
     0.446
ENSPPAP00000008479
Protein kinase domain-containing protein.
   
 
 0.443
AURKA
Aurora kinase A; Belongs to the protein kinase superfamily.
   
 
 0.443
C1orf54
Chromosome 1 open reading frame 54.
  
     0.442
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.