STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IQSEC1IQ motif and Sec7 domain 1. (1096 aa)    
Predicted Functional Partners:
ARF1
ADP ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family.
    
 
 0.955
CALM3
Calmodulin 3; Belongs to the calmodulin family.
    
 
 0.852
ARF6
Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.
    
 
 0.746
ENSPPAP00000024234
Uncharacterized protein.
    
 
 0.746
ARF5
ADP ribosylation factor 5; Belongs to the small GTPase superfamily. Arf family.
    
 
 0.704
ENSPPAP00000030581
Uncharacterized protein.
    
 
 0.681
EGFR
Receptor protein-tyrosine kinase.
   
  
 0.589
ASAP1
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1.
      
 0.553
DLG4
Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.
   
 
 0.511
GNAQ
G protein subunit alpha q.
    
 
 0.484
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.