STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRASKRAS proto-oncogene, GTPase. (189 aa)    
Predicted Functional Partners:
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1.
   
 0.985
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
   
 0.981
BRAF
B-Raf proto-oncogene, serine/threonine kinase.
   
 0.977
BCL2L1
BCL2 like 1.
    
 0.958
MAPKAP1
MAPK associated protein 1.
    
 
 0.937
RALGDS
Uncharacterized protein.
   
 0.917
PIK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
   
 0.915
RGL1
Ral guanine nucleotide dissociation stimulator like 1.
   
 0.911
EGFR
Receptor protein-tyrosine kinase.
   
 0.908
HRAS
HRas proto-oncogene, GTPase.
  
 
0.903
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.