STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CERS2Ceramide synthase 2. (380 aa)    
Predicted Functional Partners:
DEGS1
Delta 4-desaturase, sphingolipid 1.
   
 0.956
KDSR
3-ketodihydrosphingosine reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.953
ASAH1
Uncharacterized protein; Belongs to the acid ceramidase family.
    
 0.948
SMPD1
Saposin B-type domain-containing protein.
     
 0.948
ACER2
Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
    
 0.948
UGCG
UDP-glucose ceramide glucosyltransferase.
   
 
 0.947
DEGS2
Delta 4-desaturase, sphingolipid 2.
   
 0.946
SGMS1
Sphingomyelin synthase 1.
     
 0.944
CERK
Ceramide kinase.
     
 0.944
SPHK1
Sphingosine kinase 1.
     
 0.943
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.