node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ENSPPAP00000003540 | POLA2 | ENSPPAP00000003540 | ENSPPAP00000030123 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. | 0.863 |
ENSPPAP00000003540 | PRIM2 | ENSPPAP00000003540 | ENSPPAP00000000108 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | Uncharacterized protein. | 0.885 |
ENSPPAP00000003540 | RFC1 | ENSPPAP00000003540 | ENSPPAP00000038661 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | Replication factor C subunit 1. | 0.966 |
ENSPPAP00000003540 | RFC2 | ENSPPAP00000003540 | ENSPPAP00000035834 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | Replication factor C subunit 2. | 0.975 |
ENSPPAP00000003540 | RFC3 | ENSPPAP00000003540 | ENSPPAP00000017674 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | Replication factor C subunit 3. | 0.980 |
ENSPPAP00000003540 | RFC4 | ENSPPAP00000003540 | ENSPPAP00000036379 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | Replication factor C subunit 4. | 0.990 |
ENSPPAP00000003540 | RFC5 | ENSPPAP00000003540 | ENSPPAP00000042807 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | Replication factor C subunit 5. | 0.968 |
ENSPPAP00000003540 | RPA1 | ENSPPAP00000003540 | ENSPPAP00000033667 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.920 |
ENSPPAP00000003540 | WRN | ENSPPAP00000003540 | ENSPPAP00000027620 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | WRN RecQ like helicase. | 0.943 |
PCNA | POLA2 | ENSPPAP00000020249 | ENSPPAP00000030123 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. | 0.863 |
PCNA | PRIM2 | ENSPPAP00000020249 | ENSPPAP00000000108 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | Uncharacterized protein. | 0.885 |
PCNA | RFC1 | ENSPPAP00000020249 | ENSPPAP00000038661 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | Replication factor C subunit 1. | 0.994 |
PCNA | RFC2 | ENSPPAP00000020249 | ENSPPAP00000035834 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | Replication factor C subunit 2. | 0.993 |
PCNA | RFC3 | ENSPPAP00000020249 | ENSPPAP00000017674 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | Replication factor C subunit 3. | 0.988 |
PCNA | RFC4 | ENSPPAP00000020249 | ENSPPAP00000036379 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | Replication factor C subunit 4. | 0.995 |
PCNA | RFC5 | ENSPPAP00000020249 | ENSPPAP00000042807 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | Replication factor C subunit 5. | 0.990 |
PCNA | RPA1 | ENSPPAP00000020249 | ENSPPAP00000033667 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.951 |
PCNA | WRN | ENSPPAP00000020249 | ENSPPAP00000027620 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | WRN RecQ like helicase. | 0.943 |
POLA2 | ENSPPAP00000003540 | ENSPPAP00000030123 | ENSPPAP00000003540 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.863 |
POLA2 | PCNA | ENSPPAP00000030123 | ENSPPAP00000020249 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.863 |