ZMPSTE24 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FNTA	FNTB	ENSPTRP00000034622	ENSPTRP00000010932	Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha.	Protein farnesyltransferase subunit beta; Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X.	0.997
FNTA	RCE1	ENSPTRP00000034622	ENSPTRP00000006786	Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha.	RCE1 homolog, prenyl protein peptidase.	0.967
FNTA	ZMPSTE24	ENSPTRP00000034622	ENSPTRP00000080271	Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha.	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.	0.937
FNTB	FNTA	ENSPTRP00000010932	ENSPTRP00000034622	Protein farnesyltransferase subunit beta; Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X.	Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha.	0.997
FNTB	RCE1	ENSPTRP00000010932	ENSPTRP00000006786	Protein farnesyltransferase subunit beta; Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X.	RCE1 homolog, prenyl protein peptidase.	0.971
FNTB	ZMPSTE24	ENSPTRP00000010932	ENSPTRP00000080271	Protein farnesyltransferase subunit beta; Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X.	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.	0.937
ICMT	RCE1	ENSPTRP00000000148	ENSPTRP00000006786	Protein-S-isoprenylcysteine O-methyltransferase.	RCE1 homolog, prenyl protein peptidase.	0.993
ICMT	ZMPSTE24	ENSPTRP00000000148	ENSPTRP00000080271	Protein-S-isoprenylcysteine O-methyltransferase.	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.	0.969
LMNA	ZMPSTE24	ENSPTRP00000002448	ENSPTRP00000080271	LMNA isoform 8; Belongs to the intermediate filament family.	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.	0.872
NRM	ZMPSTE24	ENSPTRP00000066973	ENSPTRP00000080271	Nurim.	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.	0.697
OSBP	ZMPSTE24	ENSPTRP00000006371	ENSPTRP00000080271	Oxysterol-binding protein; Belongs to the OSBP family.	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.	0.671
PLOD1	ZMPSTE24	ENSPTRP00000077357	ENSPTRP00000080271	Procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1.	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.	0.719
RCE1	FNTA	ENSPTRP00000006786	ENSPTRP00000034622	RCE1 homolog, prenyl protein peptidase.	Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha.	0.967
RCE1	FNTB	ENSPTRP00000006786	ENSPTRP00000010932	RCE1 homolog, prenyl protein peptidase.	Protein farnesyltransferase subunit beta; Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X.	0.971
RCE1	ICMT	ENSPTRP00000006786	ENSPTRP00000000148	RCE1 homolog, prenyl protein peptidase.	Protein-S-isoprenylcysteine O-methyltransferase.	0.993
RCE1	ZMPSTE24	ENSPTRP00000006786	ENSPTRP00000080271	RCE1 homolog, prenyl protein peptidase.	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.	0.913
RPN1	ZMPSTE24	ENSPTRP00000026461	ENSPTRP00000080271	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.	0.656
SCIMP	ZMPSTE24	ENSPTRP00000014723	ENSPTRP00000080271	SCIMP isoform 1.	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.	0.709
ZMPSTE24	FNTA	ENSPTRP00000080271	ENSPTRP00000034622	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.	Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha.	0.937
ZMPSTE24	FNTB	ENSPTRP00000080271	ENSPTRP00000010932	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.	Protein farnesyltransferase subunit beta; Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X.	0.937