| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C3orf84 | TYW3 | ENSPTRP00000072868 | ENSPTRP00000001502 | Chromosome 3 open reading frame 84. | tRNA-yW synthesizing protein 3 homolog. | 0.457 |
| CK820_G0049974 | TRMT5 | ENSPTRP00000075022 | ENSPTRP00000010883 | TYW1 isoform 1. | tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. | 0.555 |
| CK820_G0049974 | TYW3 | ENSPTRP00000075022 | ENSPTRP00000001502 | TYW1 isoform 1. | tRNA-yW synthesizing protein 3 homolog. | 0.603 |
| FTSJ1 | TRMT5 | ENSPTRP00000068287 | ENSPTRP00000010883 | Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs. | tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. | 0.520 |
| FTSJ1 | TYW3 | ENSPTRP00000068287 | ENSPTRP00000001502 | Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs. | tRNA-yW synthesizing protein 3 homolog. | 0.449 |
| FTSJ1 | WDR4 | ENSPTRP00000068287 | ENSPTRP00000024006 | Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs. | tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family. | 0.639 |
| MRPL49 | TYW3 | ENSPTRP00000006665 | ENSPTRP00000001502 | Mitochondrial ribosomal protein L49. | tRNA-yW synthesizing protein 3 homolog. | 0.406 |
| TRMT5 | CK820_G0049974 | ENSPTRP00000010883 | ENSPTRP00000075022 | tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. | TYW1 isoform 1. | 0.555 |
| TRMT5 | FTSJ1 | ENSPTRP00000010883 | ENSPTRP00000068287 | tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. | Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs. | 0.520 |
| TRMT5 | TYW1B | ENSPTRP00000010883 | ENSPTRP00000047944 | tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. | TYW1B isoform 1. | 0.555 |
| TRMT5 | TYW3 | ENSPTRP00000010883 | ENSPTRP00000001502 | tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. | tRNA-yW synthesizing protein 3 homolog. | 0.696 |
| TRMT5 | TYW5 | ENSPTRP00000010883 | ENSPTRP00000039652 | tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. | Chromosome 2 open reading frame 60. | 0.423 |
| TRMT5 | WDR4 | ENSPTRP00000010883 | ENSPTRP00000024006 | tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. | tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family. | 0.458 |
| TYW1B | TRMT5 | ENSPTRP00000047944 | ENSPTRP00000010883 | TYW1B isoform 1. | tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. | 0.555 |
| TYW1B | TYW3 | ENSPTRP00000047944 | ENSPTRP00000001502 | TYW1B isoform 1. | tRNA-yW synthesizing protein 3 homolog. | 0.610 |
| TYW3 | C3orf84 | ENSPTRP00000001502 | ENSPTRP00000072868 | tRNA-yW synthesizing protein 3 homolog. | Chromosome 3 open reading frame 84. | 0.457 |
| TYW3 | CK820_G0049974 | ENSPTRP00000001502 | ENSPTRP00000075022 | tRNA-yW synthesizing protein 3 homolog. | TYW1 isoform 1. | 0.603 |
| TYW3 | FTSJ1 | ENSPTRP00000001502 | ENSPTRP00000068287 | tRNA-yW synthesizing protein 3 homolog. | Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs. | 0.449 |
| TYW3 | MRPL49 | ENSPTRP00000001502 | ENSPTRP00000006665 | tRNA-yW synthesizing protein 3 homolog. | Mitochondrial ribosomal protein L49. | 0.406 |
| TYW3 | TRMT5 | ENSPTRP00000001502 | ENSPTRP00000010883 | tRNA-yW synthesizing protein 3 homolog. | tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. | 0.696 |