| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ATR | MLH1 | ENSPTRP00000051017 | ENSPTRP00000025426 | Ataxia telangiectasia and Rad3 related; Belongs to the PI3/PI4-kinase family. | MutL homolog 1, colon cancer, nonpolyposis type 2. | 0.514 |
| ATR | MSH4 | ENSPTRP00000051017 | ENSPTRP00000084312 | Ataxia telangiectasia and Rad3 related; Belongs to the PI3/PI4-kinase family. | MSH4 isoform 1. | 0.827 |
| ATR | MSH5 | ENSPTRP00000051017 | ENSPTRP00000030697 | Ataxia telangiectasia and Rad3 related; Belongs to the PI3/PI4-kinase family. | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). | 0.676 |
| ATR | RAD51 | ENSPTRP00000051017 | ENSPTRP00000068995 | Ataxia telangiectasia and Rad3 related; Belongs to the PI3/PI4-kinase family. | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] | 0.922 |
| ATR | SPO11 | ENSPTRP00000051017 | ENSPTRP00000023491 | Ataxia telangiectasia and Rad3 related; Belongs to the PI3/PI4-kinase family. | SPO11 initiator of meiotic double stranded breaks. | 0.584 |
| ATR | TOP3A | ENSPTRP00000051017 | ENSPTRP00000046426 | Ataxia telangiectasia and Rad3 related; Belongs to the PI3/PI4-kinase family. | DNA topoisomerase III alpha. | 0.760 |
| MLH1 | ATR | ENSPTRP00000025426 | ENSPTRP00000051017 | MutL homolog 1, colon cancer, nonpolyposis type 2. | Ataxia telangiectasia and Rad3 related; Belongs to the PI3/PI4-kinase family. | 0.514 |
| MLH1 | MLH3 | ENSPTRP00000025426 | ENSPTRP00000076885 | MutL homolog 1, colon cancer, nonpolyposis type 2. | MLH3 isoform 1. | 0.991 |
| MLH1 | MSH4 | ENSPTRP00000025426 | ENSPTRP00000084312 | MutL homolog 1, colon cancer, nonpolyposis type 2. | MSH4 isoform 1. | 0.901 |
| MLH1 | MSH5 | ENSPTRP00000025426 | ENSPTRP00000030697 | MutL homolog 1, colon cancer, nonpolyposis type 2. | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). | 0.926 |
| MLH1 | PMS1 | ENSPTRP00000025426 | ENSPTRP00000066616 | MutL homolog 1, colon cancer, nonpolyposis type 2. | PMS1 homolog 1, mismatch repair system component. | 0.997 |
| MLH1 | RAD51 | ENSPTRP00000025426 | ENSPTRP00000068995 | MutL homolog 1, colon cancer, nonpolyposis type 2. | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] | 0.716 |
| MLH1 | SPO11 | ENSPTRP00000025426 | ENSPTRP00000023491 | MutL homolog 1, colon cancer, nonpolyposis type 2. | SPO11 initiator of meiotic double stranded breaks. | 0.512 |
| MLH1 | TOP3A | ENSPTRP00000025426 | ENSPTRP00000046426 | MutL homolog 1, colon cancer, nonpolyposis type 2. | DNA topoisomerase III alpha. | 0.812 |
| MLH3 | MLH1 | ENSPTRP00000076885 | ENSPTRP00000025426 | MLH3 isoform 1. | MutL homolog 1, colon cancer, nonpolyposis type 2. | 0.991 |
| MLH3 | MSH4 | ENSPTRP00000076885 | ENSPTRP00000084312 | MLH3 isoform 1. | MSH4 isoform 1. | 0.970 |
| MLH3 | MSH5 | ENSPTRP00000076885 | ENSPTRP00000030697 | MLH3 isoform 1. | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). | 0.926 |
| MLH3 | PMS1 | ENSPTRP00000076885 | ENSPTRP00000066616 | MLH3 isoform 1. | PMS1 homolog 1, mismatch repair system component. | 0.763 |
| MLH3 | RAD51 | ENSPTRP00000076885 | ENSPTRP00000068995 | MLH3 isoform 1. | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] | 0.618 |
| MLH3 | RNF212 | ENSPTRP00000076885 | ENSPTRP00000027250 | MLH3 isoform 1. | RNF212 isoform 8. | 0.689 |
