STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GBP6Guanylate binding protein family member 6. (633 aa)    
Predicted Functional Partners:
LGALS8
Galectin.
   
  
 0.718
CMPK2
Cytidine/uridine monophosphate kinase 2.
   
  
 0.601
PYHIN1
Pyrin and HIN domain family member 1.
   
  
 0.571
CLEC4E
C-type lectin domain family 4 member E.
   
  
 0.562
HERC6
Hect domain and RLD 6.
   
  
 0.533
MS4A3
Membrane spanning 4-domains A3.
      
 0.522
OAS2
2',5'-oligoadenylate synthetase 2.
   
  
 0.518
SNAPIN-2
SNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...]
      
 0.513
SNAPIN
SNAP associated protein.
      
 0.513
CDH17
CDH17 isoform 1.
      
 0.510
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.