STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BTBD8KIAA1107 isoform 1. (1409 aa)    
Predicted Functional Partners:
ENSPTRP00000001646
BTB domain containing 8.
 
     0.922
CWC15
CWC15 spliceosome-associated protein homolog.
      
 0.890
PXMP4
Peroxisomal membrane protein 4; Belongs to the peroxisomal membrane protein PXMP2/4 family.
   
  
 0.866
RNF17
RNF17 isoform 1.
      
 0.858
PPP1R3C
Protein phosphatase 1 regulatory subunit 3C; Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown.
      
 0.851
OSTN
OSTN isoform 2.
      
 0.783
PPARGC1A
PPARG coactivator 1 alpha.
   
  
 0.723
ANK3
ANK3 isoform 5.
   
 0.617
ANK2
ANK2 isoform 1.
   
 0.609
ENSPTRP00000069449
annotation not available
   
  
 0.582
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.