| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CYP2A7 | DPYD | ENSPTRP00000018915 | ENSPTRP00000001697 | CYP2A6 isoform 1; Belongs to the cytochrome P450 family. | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | 0.916 |
| CYP2A7 | TYMP | ENSPTRP00000018915 | ENSPTRP00000040056 | CYP2A6 isoform 1; Belongs to the cytochrome P450 family. | Thymidine phosphorylase. | 0.901 |
| CYP2A7 | UMPS | ENSPTRP00000018915 | ENSPTRP00000026399 | CYP2A6 isoform 1; Belongs to the cytochrome P450 family. | Uridine monophosphate synthetase. | 0.905 |
| CYP2A7 | UPP1 | ENSPTRP00000018915 | ENSPTRP00000032766 | CYP2A6 isoform 1; Belongs to the cytochrome P450 family. | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. | 0.902 |
| CYP2A7 | UPP2 | ENSPTRP00000018915 | ENSPTRP00000021460 | CYP2A6 isoform 1; Belongs to the cytochrome P450 family. | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. | 0.902 |
| DPYD | CYP2A7 | ENSPTRP00000001697 | ENSPTRP00000018915 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | CYP2A6 isoform 1; Belongs to the cytochrome P450 family. | 0.916 |
| DPYD | DPYS | ENSPTRP00000001697 | ENSPTRP00000035055 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | Dihydropyrimidinase. | 0.993 |
| DPYD | GOLT1A | ENSPTRP00000001697 | ENSPTRP00000051291 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | Golgi transport 1A. | 0.851 |
| DPYD | GOLT1B | ENSPTRP00000001697 | ENSPTRP00000008124 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | Golgi transport 1B. | 0.851 |
| DPYD | KISS1 | ENSPTRP00000001697 | ENSPTRP00000003156 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | KISS1 isoform 2. | 0.851 |
| DPYD | TYMP | ENSPTRP00000001697 | ENSPTRP00000040056 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | Thymidine phosphorylase. | 0.980 |
| DPYD | UMPS | ENSPTRP00000001697 | ENSPTRP00000026399 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | Uridine monophosphate synthetase. | 0.997 |
| DPYD | UPB1 | ENSPTRP00000001697 | ENSPTRP00000024407 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | Beta-ureidopropionase 1. | 0.932 |
| DPYD | UPP1 | ENSPTRP00000001697 | ENSPTRP00000032766 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. | 0.963 |
| DPYD | UPP2 | ENSPTRP00000001697 | ENSPTRP00000021460 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. | 0.967 |
| DPYS | DPYD | ENSPTRP00000035055 | ENSPTRP00000001697 | Dihydropyrimidinase. | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | 0.993 |
| DPYS | GOLT1A | ENSPTRP00000035055 | ENSPTRP00000051291 | Dihydropyrimidinase. | Golgi transport 1A. | 0.609 |
| DPYS | GOLT1B | ENSPTRP00000035055 | ENSPTRP00000008124 | Dihydropyrimidinase. | Golgi transport 1B. | 0.609 |
| DPYS | KISS1 | ENSPTRP00000035055 | ENSPTRP00000003156 | Dihydropyrimidinase. | KISS1 isoform 2. | 0.609 |
| DPYS | UMPS | ENSPTRP00000035055 | ENSPTRP00000026399 | Dihydropyrimidinase. | Uridine monophosphate synthetase. | 0.960 |
