STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SNX7Sorting nexin 7. (473 aa)    
Predicted Functional Partners:
GAK
Cyclin G associated kinase.
   
 0.905
SNX4
Sorting nexin 4.
  
 
 
0.861
BLOC1S2
Biogenesis of lysosomal organelles complex-1, subunit 2.
    
 
 0.821
SNX32
Sorting nexin; Involved in several stages of intracellular trafficking.
   
 0.731
SNX6
Sorting nexin; Involved in several stages of intracellular trafficking.
   
0.687
VPS35
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
   
 
 0.666
ENSPTRP00000061746
annotation not available
   
 0.653
VPS29
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
   
 
 0.651
SNX5
Sorting nexin; Involved in several stages of intracellular trafficking.
   
0.628
DNAJC6
DnaJ heat shock protein family (Hsp40) member C6.
   
 0.584
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.