DBT protein (Pan troglodytes) - STRING interaction network

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Predicted Interactions

gene neighborhood

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textmining

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protein homology

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Score

DBT

Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (507 aa)

Predicted Functional Partners:

DLD

0.999

BCKDHA

0.998

BCKDHB

0.992

IVD

0.969

PCCA

0.958

PDHB

0.952

ACADS

0.946

ACADSB

0.946

ALDH6A1

0.944

SUCLG1

0.937

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACADS	ACADSB	ENSPTRP00000009412	ENSPTRP00000077408	Acyl-CoA dehydrogenase, C-2 to C-3 short chain.	Acyl-CoA dehydrogenase, short/branched chain.	0.934
ACADS	ALDH6A1	ENSPTRP00000009412	ENSPTRP00000011082	Acyl-CoA dehydrogenase, C-2 to C-3 short chain.	Aldehyde dehydrogenase 6 family, member A1.	0.946
ACADS	BCKDHA	ENSPTRP00000009412	ENSPTRP00000018933	Acyl-CoA dehydrogenase, C-2 to C-3 short chain.	2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3); Belongs to the BCKDHA family.	0.669
ACADS	BCKDHB	ENSPTRP00000009412	ENSPTRP00000031400	Acyl-CoA dehydrogenase, C-2 to C-3 short chain.	BCKDHB isoform 1.	0.618
ACADS	DBT	ENSPTRP00000009412	ENSPTRP00000001722	Acyl-CoA dehydrogenase, C-2 to C-3 short chain.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.946
ACADS	DLD	ENSPTRP00000009412	ENSPTRP00000086612	Acyl-CoA dehydrogenase, C-2 to C-3 short chain.	Dihydrolipoyl dehydrogenase.	0.448
ACADS	PCCA	ENSPTRP00000009412	ENSPTRP00000010202	Acyl-CoA dehydrogenase, C-2 to C-3 short chain.	Propionyl CoA carboxylase, alpha polypeptide.	0.948
ACADS	SUCLG1	ENSPTRP00000009412	ENSPTRP00000020798	Acyl-CoA dehydrogenase, C-2 to C-3 short chain.	Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.	0.546
ACADSB	ACADS	ENSPTRP00000077408	ENSPTRP00000009412	Acyl-CoA dehydrogenase, short/branched chain.	Acyl-CoA dehydrogenase, C-2 to C-3 short chain.	0.934
ACADSB	ALDH6A1	ENSPTRP00000077408	ENSPTRP00000011082	Acyl-CoA dehydrogenase, short/branched chain.	Aldehyde dehydrogenase 6 family, member A1.	0.575
ACADSB	BCKDHA	ENSPTRP00000077408	ENSPTRP00000018933	Acyl-CoA dehydrogenase, short/branched chain.	2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3); Belongs to the BCKDHA family.	0.684
ACADSB	BCKDHB	ENSPTRP00000077408	ENSPTRP00000031400	Acyl-CoA dehydrogenase, short/branched chain.	BCKDHB isoform 1.	0.677
ACADSB	DBT	ENSPTRP00000077408	ENSPTRP00000001722	Acyl-CoA dehydrogenase, short/branched chain.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.946
ACADSB	DLD	ENSPTRP00000077408	ENSPTRP00000086612	Acyl-CoA dehydrogenase, short/branched chain.	Dihydrolipoyl dehydrogenase.	0.448
ACADSB	PCCA	ENSPTRP00000077408	ENSPTRP00000010202	Acyl-CoA dehydrogenase, short/branched chain.	Propionyl CoA carboxylase, alpha polypeptide.	0.520
ACADSB	SUCLG1	ENSPTRP00000077408	ENSPTRP00000020798	Acyl-CoA dehydrogenase, short/branched chain.	Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.	0.545
ALDH6A1	ACADS	ENSPTRP00000011082	ENSPTRP00000009412	Aldehyde dehydrogenase 6 family, member A1.	Acyl-CoA dehydrogenase, C-2 to C-3 short chain.	0.946
ALDH6A1	ACADSB	ENSPTRP00000011082	ENSPTRP00000077408	Aldehyde dehydrogenase 6 family, member A1.	Acyl-CoA dehydrogenase, short/branched chain.	0.575
ALDH6A1	BCKDHB	ENSPTRP00000011082	ENSPTRP00000031400	Aldehyde dehydrogenase 6 family, member A1.	BCKDHB isoform 1.	0.459
ALDH6A1	DBT	ENSPTRP00000011082	ENSPTRP00000001722	Aldehyde dehydrogenase 6 family, member A1.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.944