| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AK3 | AMPD1 | ENSPTRP00000035487 | ENSPTRP00000074005 | GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.939 |
| AK3 | AMPD2 | ENSPTRP00000035487 | ENSPTRP00000077089 | GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.938 |
| AK3 | AMPD3 | ENSPTRP00000035487 | ENSPTRP00000005861 | GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.941 |
| AK3 | APRT | ENSPTRP00000035487 | ENSPTRP00000014433 | GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. | Adenine phosphoribosyltransferase. | 0.955 |
| AK3 | ATIC | ENSPTRP00000035487 | ENSPTRP00000041425 | GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | 0.417 |
| AK3 | ENTPD1 | ENSPTRP00000035487 | ENSPTRP00000062844 | GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. | Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family. | 0.909 |
| AMPD1 | AK3 | ENSPTRP00000074005 | ENSPTRP00000035487 | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. | 0.939 |
| AMPD1 | AMPD2 | ENSPTRP00000074005 | ENSPTRP00000077089 | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.976 |
| AMPD1 | AMPD3 | ENSPTRP00000074005 | ENSPTRP00000005861 | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.977 |
| AMPD1 | APRT | ENSPTRP00000074005 | ENSPTRP00000014433 | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | Adenine phosphoribosyltransferase. | 0.979 |
| AMPD1 | ATIC | ENSPTRP00000074005 | ENSPTRP00000041425 | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | 0.948 |
| AMPD1 | ENTPD1 | ENSPTRP00000074005 | ENSPTRP00000062844 | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family. | 0.930 |
| AMPD1 | HPRT1 | ENSPTRP00000074005 | ENSPTRP00000086770 | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | Hypoxanthine-guanine phosphoribosyltransferase; Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5- phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity). | 0.954 |
| AMPD1 | IMPDH1 | ENSPTRP00000074005 | ENSPTRP00000090298 | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. | 0.931 |
| AMPD1 | IMPDH2 | ENSPTRP00000074005 | ENSPTRP00000041919 | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. | 0.940 |
| AMPD1 | LOC465053 | ENSPTRP00000074005 | ENSPTRP00000089069 | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | LOW QUALITY PROTEIN: inosine-5'-monophosphate dehydrogenase 1-like. | 0.931 |
| AMPD2 | AK3 | ENSPTRP00000077089 | ENSPTRP00000035487 | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. | 0.938 |
| AMPD2 | AMPD1 | ENSPTRP00000077089 | ENSPTRP00000074005 | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.976 |
| AMPD2 | AMPD3 | ENSPTRP00000077089 | ENSPTRP00000005861 | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.936 |
| AMPD2 | APRT | ENSPTRP00000077089 | ENSPTRP00000014433 | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | Adenine phosphoribosyltransferase. | 0.981 |
