| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADSL | ADSS1 | ENSPTRP00000093087 | ENSPTRP00000011563 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Adenylosuccinate synthetase isozyme 1 isoform X2. | 0.995 |
| ADSL | ADSS2 | ENSPTRP00000093087 | ENSPTRP00000003684 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | ADSS isoform 1. | 0.998 |
| ADSL | AK3 | ENSPTRP00000093087 | ENSPTRP00000035487 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. | 0.972 |
| ADSL | AMPD1 | ENSPTRP00000093087 | ENSPTRP00000074005 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.937 |
| ADSL | AMPD2 | ENSPTRP00000093087 | ENSPTRP00000077089 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.930 |
| ADSL | AMPD3 | ENSPTRP00000093087 | ENSPTRP00000005861 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.937 |
| ADSL | APRT | ENSPTRP00000093087 | ENSPTRP00000014433 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Adenine phosphoribosyltransferase. | 0.986 |
| ADSL | ATIC | ENSPTRP00000093087 | ENSPTRP00000041425 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | 0.999 |
| ADSL | HPRT1 | ENSPTRP00000093087 | ENSPTRP00000086770 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Hypoxanthine-guanine phosphoribosyltransferase; Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5- phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity). | 0.677 |
| ADSL | IMPDH2 | ENSPTRP00000093087 | ENSPTRP00000041919 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. | 0.690 |
| ADSS1 | ADSL | ENSPTRP00000011563 | ENSPTRP00000093087 | Adenylosuccinate synthetase isozyme 1 isoform X2. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.995 |
| ADSS1 | ADSS2 | ENSPTRP00000011563 | ENSPTRP00000003684 | Adenylosuccinate synthetase isozyme 1 isoform X2. | ADSS isoform 1. | 0.901 |
| ADSS1 | AMPD1 | ENSPTRP00000011563 | ENSPTRP00000074005 | Adenylosuccinate synthetase isozyme 1 isoform X2. | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.942 |
| ADSS1 | AMPD2 | ENSPTRP00000011563 | ENSPTRP00000077089 | Adenylosuccinate synthetase isozyme 1 isoform X2. | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.931 |
| ADSS1 | AMPD3 | ENSPTRP00000011563 | ENSPTRP00000005861 | Adenylosuccinate synthetase isozyme 1 isoform X2. | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.931 |
| ADSS1 | APRT | ENSPTRP00000011563 | ENSPTRP00000014433 | Adenylosuccinate synthetase isozyme 1 isoform X2. | Adenine phosphoribosyltransferase. | 0.657 |
| ADSS1 | ATIC | ENSPTRP00000011563 | ENSPTRP00000041425 | Adenylosuccinate synthetase isozyme 1 isoform X2. | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | 0.989 |
| ADSS1 | HPRT1 | ENSPTRP00000011563 | ENSPTRP00000086770 | Adenylosuccinate synthetase isozyme 1 isoform X2. | Hypoxanthine-guanine phosphoribosyltransferase; Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5- phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity). | 0.936 |
| ADSS1 | IMPDH2 | ENSPTRP00000011563 | ENSPTRP00000041919 | Adenylosuccinate synthetase isozyme 1 isoform X2. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. | 0.948 |
| ADSS2 | ADSL | ENSPTRP00000003684 | ENSPTRP00000093087 | ADSS isoform 1. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.998 |
