STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCL1Myeloid cell leukemia sequence 1 (BCL2-related). (350 aa)    
Predicted Functional Partners:
BCL2L11
Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family.
    
 0.999
BID
BH3-interacting domain death agonist; Counters the protective effect of Bcl-2.
   
 0.989
HUWE1
HUWE1 isoform 8.
    
 
 0.986
BAK1
BCL2-antagonist/killer 1.
    
0.946
BBC3
BCL2 binding component 3.
   
 0.938
BBC3-2
BCL2 binding component 3.
   
 0.938
ENSPTRP00000078515
annotation not available
    
 
 0.920
GZMB
GZMB isoform 2; Belongs to the peptidase S1 family.
   
 
 0.916
USP9X
Ubiquitin specific peptidase 9, X-linked; Belongs to the peptidase C19 family.
    
 
 0.911
BIK
BCL2 interacting killer.
    
 0.903
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.