STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RFX5Regulatory factor X, 5 (Influences HLA class II expression). (616 aa)    
Predicted Functional Partners:
RFXAP
Regulatory factor X associated protein.
    
 0.999
RFXANK
Regulatory factor X-associated ankyrin-containing protein.
   
 
 0.999
CIITA
Class II major histocompatibility complex transactivator.
    
 0.996
CCDC82
Coiled-coil domain containing 82.
      
 0.804
MED23
Mediator complex subunit 23.
      
 0.773
ELF4
E74-like factor 4 (Ets domain transcription factor).
      
 0.735
CREB1
cAMP responsive element binding protein 1.
   
 
 0.726
CBX3
Chromobox homolog 3.
      
 0.702
ANKRA2
Ankyrin repeat, family A (RFXANK-like), 2.
   
 
 0.697
RFX7
Regulatory factor X, 7.
    
 
0.673
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: medium (58%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.