TUFT1 protein (Pan troglodytes) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

TUFT1

TUFT1 isoform 2. (390 aa)

Predicted Functional Partners:

AMBN

0.907

KLK4

0.869

ENAM

0.835

TFIP11

0.809

AMELX

0.784

TRAPPC2

0.728

C2

0.675

AMELY

0.639

AMTN

0.638

DSPP

0.572

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMBN	AMELX	ENSPTRP00000041774	ENSPTRP00000057175	AMBN isoform 1.	Amelogenin X-linked.	0.899
AMBN	AMELY	ENSPTRP00000041774	ENSPTRP00000088203	AMBN isoform 1.	Amelogenin, Y isoform; Plays a role in biomineralization. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel (By similarity). Belongs to the amelogenin family.	0.756
AMBN	AMTN	ENSPTRP00000041774	ENSPTRP00000027734	AMBN isoform 1.	AMTN isoform 1.	0.944
AMBN	C2	ENSPTRP00000041774	ENSPTRP00000076687	AMBN isoform 1.	Complement factor B Ba fragment; Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes (By similarity).	0.405
AMBN	DSPP	ENSPTRP00000041774	ENSPTRP00000027930	AMBN isoform 1.	DSPP isoform 1.	0.801
AMBN	ENAM	ENSPTRP00000041774	ENSPTRP00000082702	AMBN isoform 1.	ENAM isoform 1.	0.969
AMBN	KLK4	ENSPTRP00000041774	ENSPTRP00000019515	AMBN isoform 1.	Kallikrein related peptidase 4; Belongs to the peptidase S1 family.	0.734
AMBN	TFIP11	ENSPTRP00000041774	ENSPTRP00000024442	AMBN isoform 1.	Tuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP- containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extrac [...]	0.516
AMBN	TUFT1	ENSPTRP00000041774	ENSPTRP00000002201	AMBN isoform 1.	TUFT1 isoform 2.	0.907
AMELX	AMBN	ENSPTRP00000057175	ENSPTRP00000041774	Amelogenin X-linked.	AMBN isoform 1.	0.899
AMELX	AMTN	ENSPTRP00000057175	ENSPTRP00000027734	Amelogenin X-linked.	AMTN isoform 1.	0.847
AMELX	DSPP	ENSPTRP00000057175	ENSPTRP00000027930	Amelogenin X-linked.	DSPP isoform 1.	0.563
AMELX	ENAM	ENSPTRP00000057175	ENSPTRP00000082702	Amelogenin X-linked.	ENAM isoform 1.	0.901
AMELX	KLK4	ENSPTRP00000057175	ENSPTRP00000019515	Amelogenin X-linked.	Kallikrein related peptidase 4; Belongs to the peptidase S1 family.	0.699
AMELX	TFIP11	ENSPTRP00000057175	ENSPTRP00000024442	Amelogenin X-linked.	Tuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP- containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extrac [...]	0.459
AMELX	TUFT1	ENSPTRP00000057175	ENSPTRP00000002201	Amelogenin X-linked.	TUFT1 isoform 2.	0.784
AMELY	AMBN	ENSPTRP00000088203	ENSPTRP00000041774	Amelogenin, Y isoform; Plays a role in biomineralization. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel (By similarity). Belongs to the amelogenin family.	AMBN isoform 1.	0.756
AMELY	AMTN	ENSPTRP00000088203	ENSPTRP00000027734	Amelogenin, Y isoform; Plays a role in biomineralization. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel (By similarity). Belongs to the amelogenin family.	AMTN isoform 1.	0.648
AMELY	DSPP	ENSPTRP00000088203	ENSPTRP00000027930	Amelogenin, Y isoform; Plays a role in biomineralization. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel (By similarity). Belongs to the amelogenin family.	DSPP isoform 1.	0.446
AMELY	ENAM	ENSPTRP00000088203	ENSPTRP00000082702	Amelogenin, Y isoform; Plays a role in biomineralization. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel (By similarity). Belongs to the amelogenin family.	ENAM isoform 1.	0.769