STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
S100A9Protein S100; Belongs to the S-100 family. (114 aa)    
Predicted Functional Partners:
S100A8
Protein S100; Belongs to the S-100 family.
  
0.999
S100A12
S100 calcium binding protein A12; Belongs to the S-100 family.
  
 
0.962
TLR4
Toll-like receptor 4; Belongs to the Toll-like receptor family.
   
 0.775
LY96
Lymphocyte antigen 96.
   
 
 0.688
AGER
Advanced glycosylation end-product specific receptor.
   
 0.659
S100A7
Protein S100; Belongs to the S-100 family.
   
 0.659
HSPA9
Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family.
    
 0.653
TLR2
Toll-like receptor 2; Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). May also promote apoptosis in response to lipoproteins. Forms activation clusters composed of several receptors depending on the ligand, these clusters trigger signaling from the cell surface and subsequentl [...]
   
 0.651
CAMP
Cathelicidin antimicrobial peptide; Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity; Belongs to the cathelicidin family.
   
 
 0.639
CD36
CD36 molecule (Thrombospondin receptor); Belongs to the CD36 family.
   
 0.594
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.