RGS4 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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same PNG format, but at higher resolution

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C11H11orf87	RGS4	ENSPTRP00000089863	ENSPTRP00000002692	Chromosome 11 open reading frame 87.	Regulator of G protein signaling 4.	0.723
EGFR	GNAI3	ENSPTRP00000069741	ENSPTRP00000001821	Receptor protein-tyrosine kinase.	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3.	0.581
EGFR	RGS4	ENSPTRP00000069741	ENSPTRP00000002692	Receptor protein-tyrosine kinase.	Regulator of G protein signaling 4.	0.814
ENSPTRP00000075783	GNAI1	ENSPTRP00000075783	ENSPTRP00000071974	annotation not available	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1.	0.676
ENSPTRP00000075783	GNAI2	ENSPTRP00000075783	ENSPTRP00000025802	annotation not available	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2.	0.556
ENSPTRP00000075783	GNAI3	ENSPTRP00000075783	ENSPTRP00000001821	annotation not available	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3.	0.787
ENSPTRP00000075783	GNAO1	ENSPTRP00000075783	ENSPTRP00000088044	annotation not available	G protein subunit alpha o1.	0.550
ENSPTRP00000075783	RGS4	ENSPTRP00000075783	ENSPTRP00000002692	annotation not available	Regulator of G protein signaling 4.	0.844
ENSPTRP00000077377	GNAI1	ENSPTRP00000077377	ENSPTRP00000071974	annotation not available	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1.	0.502
ENSPTRP00000077377	GNAI3	ENSPTRP00000077377	ENSPTRP00000001821	annotation not available	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3.	0.673
ENSPTRP00000077377	RGS4	ENSPTRP00000077377	ENSPTRP00000002692	annotation not available	Regulator of G protein signaling 4.	0.844
GNAI1	ENSPTRP00000075783	ENSPTRP00000071974	ENSPTRP00000075783	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1.	annotation not available	0.676
GNAI1	ENSPTRP00000077377	ENSPTRP00000071974	ENSPTRP00000077377	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1.	annotation not available	0.502
GNAI1	GNAI2	ENSPTRP00000071974	ENSPTRP00000025802	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1.	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2.	0.999
GNAI1	GNAI3	ENSPTRP00000071974	ENSPTRP00000001821	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1.	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3.	0.999
GNAI1	GNAO1	ENSPTRP00000071974	ENSPTRP00000088044	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1.	G protein subunit alpha o1.	0.894
GNAI1	GNAQ	ENSPTRP00000071974	ENSPTRP00000049267	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1.	Guanine nucleotide binding protein (G protein), q polypeptide.	0.683
GNAI1	RGS4	ENSPTRP00000071974	ENSPTRP00000002692	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1.	Regulator of G protein signaling 4.	0.810
GNAI2	ENSPTRP00000075783	ENSPTRP00000025802	ENSPTRP00000075783	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2.	annotation not available	0.556
GNAI2	GNAI1	ENSPTRP00000025802	ENSPTRP00000071974	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2.	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1.	0.999