Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene Fusion
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[Homology]
Score
MGST3Microsomal glutathione S-transferase 3. (165 aa)    
Predicted Functional Partners:
MGST1-2
Microsomal glutathione S-transferase 1.
   
 
 0.942
MGST2
Microsomal glutathione S-transferase 2.
     
0.907
AS3MT
Arsenite methyltransferase.
    
  0.903
MGST1
Microsomal glutathione S-transferase 1.
   
 
 0.844
EPHX1
Epoxide hydrolase; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Belongs to the peptidase S33 family.
    
 0.760
GSR
Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
     
 0.753
GSTP1
Glutathione S-transferase pi 1; Belongs to the GST superfamily.
   
 
 0.753
HPGDS
Hematopoietic prostaglandin D synthase; Belongs to the GST superfamily.
   
 
 0.742
GSTO1
Glutathione S-transferase omega 1.
   
 
 0.736
ENSPTRP00000082718
annotation not available
   
 
 0.736
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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