MGST3 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

MGST3

Microsomal glutathione S-transferase 3. (165 aa)

Predicted Functional Partners:

MGST1

0.935

CYP2E1

0.928

EPHX1

0.924

GPX4

0.920

GSR

0.918

TXNDC12

0.906

CHAC1

0.905

CYP2C9

0.903

LOC101058187

0.903

PRDX6

0.902

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHAC1	GPX4	ENSPTRP00000079119	ENSPTRP00000049169	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.943
CHAC1	GSR	ENSPTRP00000079119	ENSPTRP00000034471	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	0.900
CHAC1	MGST1	ENSPTRP00000079119	ENSPTRP00000069631	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	Microsomal glutathione S-transferase 1.	0.900
CHAC1	MGST3	ENSPTRP00000079119	ENSPTRP00000002704	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	Microsomal glutathione S-transferase 3.	0.905
CHAC1	PRDX6	ENSPTRP00000079119	ENSPTRP00000060423	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	PRDX6 isoform 1.	0.900
CHAC1	TXNDC12	ENSPTRP00000079119	ENSPTRP00000001261	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	Thioredoxin domain containing 12 (Endoplasmic reticulum).	0.901
CYP2C9	CYP2E1	ENSPTRP00000004853	ENSPTRP00000005465	Cytochrome P450 family 2 subfamily C member 9; Belongs to the cytochrome P450 family.	Cytochrome P450 family 2 subfamily E member 1; Belongs to the cytochrome P450 family.	0.926
CYP2C9	EPHX1	ENSPTRP00000004853	ENSPTRP00000003444	Cytochrome P450 family 2 subfamily C member 9; Belongs to the cytochrome P450 family.	Epoxide hydrolase; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Belongs to the peptidase S33 family.	0.947
CYP2C9	MGST1	ENSPTRP00000004853	ENSPTRP00000069631	Cytochrome P450 family 2 subfamily C member 9; Belongs to the cytochrome P450 family.	Microsomal glutathione S-transferase 1.	0.900
CYP2C9	MGST3	ENSPTRP00000004853	ENSPTRP00000002704	Cytochrome P450 family 2 subfamily C member 9; Belongs to the cytochrome P450 family.	Microsomal glutathione S-transferase 3.	0.903
CYP2E1	CYP2C9	ENSPTRP00000005465	ENSPTRP00000004853	Cytochrome P450 family 2 subfamily E member 1; Belongs to the cytochrome P450 family.	Cytochrome P450 family 2 subfamily C member 9; Belongs to the cytochrome P450 family.	0.926
CYP2E1	EPHX1	ENSPTRP00000005465	ENSPTRP00000003444	Cytochrome P450 family 2 subfamily E member 1; Belongs to the cytochrome P450 family.	Epoxide hydrolase; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Belongs to the peptidase S33 family.	0.955
CYP2E1	LOC101058187	ENSPTRP00000005465	ENSPTRP00000048703	Cytochrome P450 family 2 subfamily E member 1; Belongs to the cytochrome P450 family.	CYP2A13 isoform 1; Belongs to the cytochrome P450 family.	0.922
CYP2E1	MGST1	ENSPTRP00000005465	ENSPTRP00000069631	Cytochrome P450 family 2 subfamily E member 1; Belongs to the cytochrome P450 family.	Microsomal glutathione S-transferase 1.	0.911
CYP2E1	MGST3	ENSPTRP00000005465	ENSPTRP00000002704	Cytochrome P450 family 2 subfamily E member 1; Belongs to the cytochrome P450 family.	Microsomal glutathione S-transferase 3.	0.928
EPHX1	CYP2C9	ENSPTRP00000003444	ENSPTRP00000004853	Epoxide hydrolase; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Belongs to the peptidase S33 family.	Cytochrome P450 family 2 subfamily C member 9; Belongs to the cytochrome P450 family.	0.947
EPHX1	CYP2E1	ENSPTRP00000003444	ENSPTRP00000005465	Epoxide hydrolase; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Belongs to the peptidase S33 family.	Cytochrome P450 family 2 subfamily E member 1; Belongs to the cytochrome P450 family.	0.955
EPHX1	LOC101058187	ENSPTRP00000003444	ENSPTRP00000048703	Epoxide hydrolase; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Belongs to the peptidase S33 family.	CYP2A13 isoform 1; Belongs to the cytochrome P450 family.	0.919
EPHX1	MGST1	ENSPTRP00000003444	ENSPTRP00000069631	Epoxide hydrolase; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Belongs to the peptidase S33 family.	Microsomal glutathione S-transferase 1.	0.921
EPHX1	MGST3	ENSPTRP00000003444	ENSPTRP00000002704	Epoxide hydrolase; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Belongs to the peptidase S33 family.	Microsomal glutathione S-transferase 3.	0.924