STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SELLL-selectin; Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia; Belongs to the selectin/LECAM family. (385 aa)    
Predicted Functional Partners:
CD34
CD34 isoform 1.
   
 
 0.995
CD44
CD44 isoform 3.
   
 0.974
SELPLG
SELPLG isoform 2.
   
 0.951
CALM3
Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family.
    
 
 0.892
CCR7
C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.882
CD4
T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]
   
 0.838
CD69
CD69 isoform 3.
   
  
 0.837
SELE
SELE isoform 1.
  
 
0.827
SELP
SELP isoform 2.
  
 
0.824
CALM1
CALM1 isoform 3; Belongs to the calmodulin family.
    
 
 0.823
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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