STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MR1Major histocompatibility complex class I-related gene protein; Antigen-presenting molecule specialized in presenting microbial vitamin B metabolites. Involved in the development and expansion of a small population of T-cells expressing an invariant T- cell receptor alpha chain called mucosal-associated invariant T-cells (MAIT). MAIT lymphocytes are preferentially located in the gut lamina propria and therefore may be involved in monitoring commensal flora or serve as a distress signal. Expression and MAIT cell recognition seem to be ligand-dependent (By similarity); Belongs to the MHC [...] (341 aa)    
Predicted Functional Partners:
CD8A
CD8A isoform 1.
   
 0.891
B2M
Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).
   
 0.836
PATR-E
Patr class I histocompatibility antigen, alpha chain E; Preferably binds to a peptide derived from the signal sequence of most HLA-A, -B, -C and -G molecules.
  
 
 
0.738
PATR-G
Patr class I histocompatibility antigen, alpha chain G; Involved in the presentation of foreign antigens to the immune system.
  
0.677
PATR-B
Patr class I histocompatibility antigen, C alpha chain; Involved in the presentation of foreign antigens to the immune system.
  
0.656
ENSPTRP00000066250
annotation not available
   
 0.644
RPA2
Replication protein A2, 32kDa.
   
 0.644
PATR-DRA
MHC class II protein; Belongs to the MHC class II family.
   
 
 0.624
HLA-DOA
Major histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family.
   
 
 0.608
HLA-A
Patr class I histocompatibility antigen, A-108 alpha chain; Involved in the presentation of foreign antigens to the immune system.
  
 
 
0.603
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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