| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGO2 | DDX5 | ENSPTRP00000035263 | ENSPTRP00000016210 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Probable ATP-dependent RNA helicase DDX5; Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre- mRNA in the stem-loop region downstream of exon 10. The rate of ATP hydrolysis is highly stimulated by single-stranded RNA. Involved in transcriptional regulation; the function is independent of the RNA helicase activity. Transcriptional coactivator for androgen receptor AR but probably not ESR1. Synergizes with DDX17 and SRA1 RNA to activate MYOD1 t [...] | 0.433 |
| AGO2 | DHX9 | ENSPTRP00000035263 | ENSPTRP00000002937 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | DEAH (Asp-Glu-Ala-His) box polypeptide 9. | 0.874 |
| AGO2 | HNRNPA2B1 | ENSPTRP00000035263 | ENSPTRP00000032472 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Heterogeneous nuclear ribonucleoprotein A2/B1. | 0.624 |
| DDX17 | DDX5 | ENSPTRP00000062822 | ENSPTRP00000016210 | DEAD-box helicase 17; Belongs to the DEAD box helicase family. | Probable ATP-dependent RNA helicase DDX5; Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre- mRNA in the stem-loop region downstream of exon 10. The rate of ATP hydrolysis is highly stimulated by single-stranded RNA. Involved in transcriptional regulation; the function is independent of the RNA helicase activity. Transcriptional coactivator for androgen receptor AR but probably not ESR1. Synergizes with DDX17 and SRA1 RNA to activate MYOD1 t [...] | 0.995 |
| DDX17 | DHX9 | ENSPTRP00000062822 | ENSPTRP00000002937 | DEAD-box helicase 17; Belongs to the DEAD box helicase family. | DEAH (Asp-Glu-Ala-His) box polypeptide 9. | 0.875 |
| DDX17 | ENSPTRP00000074420 | ENSPTRP00000062822 | ENSPTRP00000074420 | DEAD-box helicase 17; Belongs to the DEAD box helicase family. | annotation not available | 0.613 |
| DDX17 | FUS | ENSPTRP00000062822 | ENSPTRP00000053592 | DEAD-box helicase 17; Belongs to the DEAD box helicase family. | FUS isoform 7. | 0.899 |
| DDX17 | HNRNPA2B1 | ENSPTRP00000062822 | ENSPTRP00000032472 | DEAD-box helicase 17; Belongs to the DEAD box helicase family. | Heterogeneous nuclear ribonucleoprotein A2/B1. | 0.544 |
| DDX17 | HNRNPU | ENSPTRP00000062822 | ENSPTRP00000084872 | DEAD-box helicase 17; Belongs to the DEAD box helicase family. | Heterogeneous nuclear ribonucleoprotein U (Scaffold attachment factor A). | 0.672 |
| DDX21 | DHX9 | ENSPTRP00000004431 | ENSPTRP00000002937 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 21. | DEAH (Asp-Glu-Ala-His) box polypeptide 9. | 0.941 |
| DDX21 | ENSPTRP00000074420 | ENSPTRP00000004431 | ENSPTRP00000074420 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 21. | annotation not available | 0.743 |
| DDX21 | HNRNPA2B1 | ENSPTRP00000004431 | ENSPTRP00000032472 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 21. | Heterogeneous nuclear ribonucleoprotein A2/B1. | 0.460 |
| DDX21 | HNRNPU | ENSPTRP00000004431 | ENSPTRP00000084872 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 21. | Heterogeneous nuclear ribonucleoprotein U (Scaffold attachment factor A). | 0.734 |
| DDX21 | ILF3 | ENSPTRP00000004431 | ENSPTRP00000079241 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 21. | Interleukin enhancer binding factor 3, 90kDa. | 0.427 |
| DDX5 | AGO2 | ENSPTRP00000016210 | ENSPTRP00000035263 | Probable ATP-dependent RNA helicase DDX5; Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre- mRNA in the stem-loop region downstream of exon 10. The rate of ATP hydrolysis is highly stimulated by single-stranded RNA. Involved in transcriptional regulation; the function is independent of the RNA helicase activity. Transcriptional coactivator for androgen receptor AR but probably not ESR1. Synergizes with DDX17 and SRA1 RNA to activate MYOD1 t [...] | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | 0.433 |
| DDX5 | DDX17 | ENSPTRP00000016210 | ENSPTRP00000062822 | Probable ATP-dependent RNA helicase DDX5; Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre- mRNA in the stem-loop region downstream of exon 10. The rate of ATP hydrolysis is highly stimulated by single-stranded RNA. Involved in transcriptional regulation; the function is independent of the RNA helicase activity. Transcriptional coactivator for androgen receptor AR but probably not ESR1. Synergizes with DDX17 and SRA1 RNA to activate MYOD1 t [...] | DEAD-box helicase 17; Belongs to the DEAD box helicase family. | 0.995 |
| DDX5 | DHX9 | ENSPTRP00000016210 | ENSPTRP00000002937 | Probable ATP-dependent RNA helicase DDX5; Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre- mRNA in the stem-loop region downstream of exon 10. The rate of ATP hydrolysis is highly stimulated by single-stranded RNA. Involved in transcriptional regulation; the function is independent of the RNA helicase activity. Transcriptional coactivator for androgen receptor AR but probably not ESR1. Synergizes with DDX17 and SRA1 RNA to activate MYOD1 t [...] | DEAH (Asp-Glu-Ala-His) box polypeptide 9. | 0.958 |
| DDX5 | ENSPTRP00000074420 | ENSPTRP00000016210 | ENSPTRP00000074420 | Probable ATP-dependent RNA helicase DDX5; Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre- mRNA in the stem-loop region downstream of exon 10. The rate of ATP hydrolysis is highly stimulated by single-stranded RNA. Involved in transcriptional regulation; the function is independent of the RNA helicase activity. Transcriptional coactivator for androgen receptor AR but probably not ESR1. Synergizes with DDX17 and SRA1 RNA to activate MYOD1 t [...] | annotation not available | 0.923 |
| DDX5 | FUS | ENSPTRP00000016210 | ENSPTRP00000053592 | Probable ATP-dependent RNA helicase DDX5; Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre- mRNA in the stem-loop region downstream of exon 10. The rate of ATP hydrolysis is highly stimulated by single-stranded RNA. Involved in transcriptional regulation; the function is independent of the RNA helicase activity. Transcriptional coactivator for androgen receptor AR but probably not ESR1. Synergizes with DDX17 and SRA1 RNA to activate MYOD1 t [...] | FUS isoform 7. | 0.902 |
| DDX5 | HNRNPA2B1 | ENSPTRP00000016210 | ENSPTRP00000032472 | Probable ATP-dependent RNA helicase DDX5; Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre- mRNA in the stem-loop region downstream of exon 10. The rate of ATP hydrolysis is highly stimulated by single-stranded RNA. Involved in transcriptional regulation; the function is independent of the RNA helicase activity. Transcriptional coactivator for androgen receptor AR but probably not ESR1. Synergizes with DDX17 and SRA1 RNA to activate MYOD1 t [...] | Heterogeneous nuclear ribonucleoprotein A2/B1. | 0.943 |
