GPR37L1 protein (Pan troglodytes) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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co-expression

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gene neighborhood

gene co-occurrence

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Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GPR37L1	GPR39	ENSPTRP00000003086	ENSPTRP00000021350	G protein-coupled receptor 37 like 1.	G protein-coupled receptor 39; Belongs to the G-protein coupled receptor 1 family.	0.567
GPR37L1	GRIN3A	ENSPTRP00000003086	ENSPTRP00000039833	G protein-coupled receptor 37 like 1.	GRIN3A isoform 1.	0.568
GPR37L1	LUM	ENSPTRP00000003086	ENSPTRP00000008987	G protein-coupled receptor 37 like 1.	LUM isoform 1.	0.560
GPR37L1	MCM7	ENSPTRP00000003086	ENSPTRP00000033323	G protein-coupled receptor 37 like 1.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.557
GPR37L1	MLN	ENSPTRP00000003086	ENSPTRP00000077901	G protein-coupled receptor 37 like 1.	MLN isoform 2.	0.578
GPR37L1	NACC2	ENSPTRP00000003086	ENSPTRP00000036890	G protein-coupled receptor 37 like 1.	NACC2 isoform 1.	0.557
GPR37L1	PRKN	ENSPTRP00000003086	ENSPTRP00000032068	G protein-coupled receptor 37 like 1.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.714
GPR37L1	PSAP	ENSPTRP00000003086	ENSPTRP00000064944	G protein-coupled receptor 37 like 1.	Prosaposin; Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling.	0.914
GPR37L1	PSAPL1	ENSPTRP00000003086	ENSPTRP00000053714	G protein-coupled receptor 37 like 1.	Proactivator polypeptide-like 1; May activate the lysosomal degradation of sphingolipids.	0.869
GPR37L1	RPS6KB2	ENSPTRP00000003086	ENSPTRP00000006810	G protein-coupled receptor 37 like 1.	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	0.622
GPR39	GPR37L1	ENSPTRP00000021350	ENSPTRP00000003086	G protein-coupled receptor 39; Belongs to the G-protein coupled receptor 1 family.	G protein-coupled receptor 37 like 1.	0.567
GPR39	MLN	ENSPTRP00000021350	ENSPTRP00000077901	G protein-coupled receptor 39; Belongs to the G-protein coupled receptor 1 family.	MLN isoform 2.	0.734
GPR39	PSAP	ENSPTRP00000021350	ENSPTRP00000064944	G protein-coupled receptor 39; Belongs to the G-protein coupled receptor 1 family.	Prosaposin; Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling.	0.646
GRIN3A	GPR37L1	ENSPTRP00000039833	ENSPTRP00000003086	GRIN3A isoform 1.	G protein-coupled receptor 37 like 1.	0.568
GRIN3A	LUM	ENSPTRP00000039833	ENSPTRP00000008987	GRIN3A isoform 1.	LUM isoform 1.	0.829
GRIN3A	MCM7	ENSPTRP00000039833	ENSPTRP00000033323	GRIN3A isoform 1.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.825
LUM	GPR37L1	ENSPTRP00000008987	ENSPTRP00000003086	LUM isoform 1.	G protein-coupled receptor 37 like 1.	0.560
LUM	GRIN3A	ENSPTRP00000008987	ENSPTRP00000039833	LUM isoform 1.	GRIN3A isoform 1.	0.829
LUM	MCM7	ENSPTRP00000008987	ENSPTRP00000033323	LUM isoform 1.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.815
MCM7	GPR37L1	ENSPTRP00000033323	ENSPTRP00000003086	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	G protein-coupled receptor 37 like 1.	0.557