STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLXNA2PLXNA2 isoform 1. (1909 aa)    
Predicted Functional Partners:
NRP1
Neuropilin; Belongs to the neuropilin family.
    
 0.996
RND1
RND1 isoform 1.
    
 0.992
SEMA3A
SEMA3A isoform 1; Belongs to the semaphorin family.
    
 0.980
SEMA6A
SEMA6A isoform 2; Belongs to the semaphorin family.
    
0.977
RHOD-2
Ras homolog family member D.
    
 0.936
FYN
Tyrosine-protein kinase.
   
 0.932
SEMA6B
Sema domain, transmembrane domain (TM), and cytoplasmic domain, (Semaphorin) 6B; Belongs to the semaphorin family.
    
 0.894
SEMA4D
SEMA4D isoform 13; Belongs to the semaphorin family.
    
 0.863
SEMA6D
Sema domain, transmembrane domain (TM), and cytoplasmic domain, (Semaphorin) 6D; Belongs to the semaphorin family.
    
0.803
SEMA3B
SEMA3B isoform 2; Belongs to the semaphorin family.
    
 0.803
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.