node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AKR1C4 | AKR1D1 | ENSPTRP00000003803 | ENSPTRP00000033814 | Aldo-keto reductase family 1 member C4. | Aldo-keto reductase family 1 member D1. | 0.940 |
AKR1C4 | HSD11B1 | ENSPTRP00000003803 | ENSPTRP00000003270 | Aldo-keto reductase family 1 member C4. | Hydroxysteroid (11-beta) dehydrogenase 1. | 0.932 |
AKR1C4 | HSD3B2 | ENSPTRP00000003803 | ENSPTRP00000051923 | Aldo-keto reductase family 1 member C4. | Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2; Belongs to the 3-beta-HSD family. | 0.511 |
AKR1D1 | AKR1C4 | ENSPTRP00000033814 | ENSPTRP00000003803 | Aldo-keto reductase family 1 member D1. | Aldo-keto reductase family 1 member C4. | 0.940 |
AKR1D1 | HSD11B1 | ENSPTRP00000033814 | ENSPTRP00000003270 | Aldo-keto reductase family 1 member D1. | Hydroxysteroid (11-beta) dehydrogenase 1. | 0.959 |
AKR1D1 | HSD11B2 | ENSPTRP00000033814 | ENSPTRP00000014053 | Aldo-keto reductase family 1 member D1. | Hydroxysteroid 11-beta dehydrogenase 2. | 0.957 |
AKR1D1 | HSD3B1 | ENSPTRP00000033814 | ENSPTRP00000002008 | Aldo-keto reductase family 1 member D1. | Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1; Belongs to the 3-beta-HSD family. | 0.913 |
AKR1D1 | HSD3B2 | ENSPTRP00000033814 | ENSPTRP00000051923 | Aldo-keto reductase family 1 member D1. | Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2; Belongs to the 3-beta-HSD family. | 0.924 |
AKR1D1 | LOC745345 | ENSPTRP00000033814 | ENSPTRP00000071445 | Aldo-keto reductase family 1 member D1. | CYP21A2 isoform 1; Belongs to the cytochrome P450 family. | 0.902 |
CYP1A1 | CYP2D6 | ENSPTRP00000058539 | ENSPTRP00000042793 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 2D6; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids, steroids and retinoids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the epoxidation of double bonds of polyunsaturated fatty acids (PUFA). Metabolizes endocannabinoid arachidonoylethanolamide (anandamide) to 20-hydroxyeicosatetraenoic acid ethanolamide (20-HETE-EA) and 8,9-, 11,12-, and 14,15-epoxyei [...] | 0.931 |
CYP1A1 | CYP2E1 | ENSPTRP00000058539 | ENSPTRP00000005465 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 family 2 subfamily E member 1; Belongs to the cytochrome P450 family. | 0.935 |
CYP1A1 | CYP3A4 | ENSPTRP00000058539 | ENSPTRP00000081767 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 family 3 subfamily A member 4. | 0.977 |
CYP1A1 | HSD11B1 | ENSPTRP00000058539 | ENSPTRP00000003270 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Hydroxysteroid (11-beta) dehydrogenase 1. | 0.924 |
CYP1A1 | HSD3B1 | ENSPTRP00000058539 | ENSPTRP00000002008 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1; Belongs to the 3-beta-HSD family. | 0.930 |
CYP1A1 | HSD3B2 | ENSPTRP00000058539 | ENSPTRP00000051923 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2; Belongs to the 3-beta-HSD family. | 0.956 |
CYP2D6 | CYP1A1 | ENSPTRP00000042793 | ENSPTRP00000058539 | Cytochrome P450 2D6; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids, steroids and retinoids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the epoxidation of double bonds of polyunsaturated fatty acids (PUFA). Metabolizes endocannabinoid arachidonoylethanolamide (anandamide) to 20-hydroxyeicosatetraenoic acid ethanolamide (20-HETE-EA) and 8,9-, 11,12-, and 14,15-epoxyei [...] | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | 0.931 |
CYP2D6 | CYP3A4 | ENSPTRP00000042793 | ENSPTRP00000081767 | Cytochrome P450 2D6; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids, steroids and retinoids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the epoxidation of double bonds of polyunsaturated fatty acids (PUFA). Metabolizes endocannabinoid arachidonoylethanolamide (anandamide) to 20-hydroxyeicosatetraenoic acid ethanolamide (20-HETE-EA) and 8,9-, 11,12-, and 14,15-epoxyei [...] | Cytochrome P450 family 3 subfamily A member 4. | 0.949 |
CYP2D6 | HSD11B1 | ENSPTRP00000042793 | ENSPTRP00000003270 | Cytochrome P450 2D6; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids, steroids and retinoids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the epoxidation of double bonds of polyunsaturated fatty acids (PUFA). Metabolizes endocannabinoid arachidonoylethanolamide (anandamide) to 20-hydroxyeicosatetraenoic acid ethanolamide (20-HETE-EA) and 8,9-, 11,12-, and 14,15-epoxyei [...] | Hydroxysteroid (11-beta) dehydrogenase 1. | 0.923 |
CYP2E1 | CYP1A1 | ENSPTRP00000005465 | ENSPTRP00000058539 | Cytochrome P450 family 2 subfamily E member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | 0.935 |
CYP2E1 | CYP3A4 | ENSPTRP00000005465 | ENSPTRP00000081767 | Cytochrome P450 family 2 subfamily E member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 family 3 subfamily A member 4. | 0.979 |