HHAT protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AASDH	HHAT	ENSPTRP00000081923	ENSPTRP00000092641	Aminoadipate-semialdehyde dehydrogenase.	Hedgehog acyltransferase; Belongs to the membrane-bound acyltransferase family.	0.619
AASDH	HHATL	ENSPTRP00000081923	ENSPTRP00000048449	Aminoadipate-semialdehyde dehydrogenase.	Hedgehog acyltransferase like; Belongs to the membrane-bound acyltransferase family.	0.619
ATP1B1	GJA10	ENSPTRP00000002750	ENSPTRP00000031472	Sodium/potassium-transporting ATPase subunit beta-1; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane (By similarity).	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	0.610
ATP1B1	HHAT	ENSPTRP00000002750	ENSPTRP00000092641	Sodium/potassium-transporting ATPase subunit beta-1; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane (By similarity).	Hedgehog acyltransferase; Belongs to the membrane-bound acyltransferase family.	0.623
ATP1B1	ZNF169	ENSPTRP00000002750	ENSPTRP00000036119	Sodium/potassium-transporting ATPase subunit beta-1; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane (By similarity).	Zinc finger protein 169.	0.422
DHH	HHAT	ENSPTRP00000075048	ENSPTRP00000092641	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Hedgehog acyltransferase; Belongs to the membrane-bound acyltransferase family.	0.830
DHH	HHATL	ENSPTRP00000075048	ENSPTRP00000048449	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Hedgehog acyltransferase like; Belongs to the membrane-bound acyltransferase family.	0.566
DHH	IHH	ENSPTRP00000075048	ENSPTRP00000022106	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.935
DHH	SHH	ENSPTRP00000075048	ENSPTRP00000075730	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.933
GJA10	ATP1B1	ENSPTRP00000031472	ENSPTRP00000002750	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	Sodium/potassium-transporting ATPase subunit beta-1; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane (By similarity).	0.610
GJA10	HHAT	ENSPTRP00000031472	ENSPTRP00000092641	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	Hedgehog acyltransferase; Belongs to the membrane-bound acyltransferase family.	0.707
GJA10	ZNF169	ENSPTRP00000031472	ENSPTRP00000036119	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	Zinc finger protein 169.	0.520
HHAT	AASDH	ENSPTRP00000092641	ENSPTRP00000081923	Hedgehog acyltransferase; Belongs to the membrane-bound acyltransferase family.	Aminoadipate-semialdehyde dehydrogenase.	0.619
HHAT	ATP1B1	ENSPTRP00000092641	ENSPTRP00000002750	Hedgehog acyltransferase; Belongs to the membrane-bound acyltransferase family.	Sodium/potassium-transporting ATPase subunit beta-1; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane (By similarity).	0.623
HHAT	DHH	ENSPTRP00000092641	ENSPTRP00000075048	Hedgehog acyltransferase; Belongs to the membrane-bound acyltransferase family.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.830
HHAT	GJA10	ENSPTRP00000092641	ENSPTRP00000031472	Hedgehog acyltransferase; Belongs to the membrane-bound acyltransferase family.	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	0.707
HHAT	HHATL	ENSPTRP00000092641	ENSPTRP00000048449	Hedgehog acyltransferase; Belongs to the membrane-bound acyltransferase family.	Hedgehog acyltransferase like; Belongs to the membrane-bound acyltransferase family.	0.905
HHAT	IHH	ENSPTRP00000092641	ENSPTRP00000022106	Hedgehog acyltransferase; Belongs to the membrane-bound acyltransferase family.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.791
HHAT	MBOAT2	ENSPTRP00000092641	ENSPTRP00000020007	Hedgehog acyltransferase; Belongs to the membrane-bound acyltransferase family.	Membrane bound O-acyltransferase domain containing 2; Belongs to the membrane-bound acyltransferase family.	0.552
HHAT	PORCN	ENSPTRP00000092641	ENSPTRP00000061755	Hedgehog acyltransferase; Belongs to the membrane-bound acyltransferase family.	Porcupine O-acyltransferase; Belongs to the membrane-bound acyltransferase family.	0.559