STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NEK2NIMA (Never in mitosis gene a)-related kinase 2. (445 aa)    
Predicted Functional Partners:
ANAPC4
Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family.
    
 0.998
BUB1B
BUB1B-PAK6 isoform 4.
   
 0.998
FZR1
Fizzy and cell division cycle 20 related 1.
   
 0.994
CDC20
Cell division cycle 20 homolog.
   
 0.975
CDC23
Cell division cycle 23 homolog.
    
 0.975
LOC737111
Cell division cycle protein 20 homolog pseudogene.
   
 0.975
CDC16
Cell division cycle 16 homolog.
    
 0.967
ANAPC2
Anaphase promoting complex subunit 2; Belongs to the cullin family.
    
  0.961
CDC26
Cell division cycle 26 homolog.
    
 0.956
MAD2L1
MAD2 mitotic arrest deficient-like 1.
   
 0.950
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.