STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (486 aa)    
Predicted Functional Partners:
PPP2R1B
Protein phosphatase 2 scaffold subunit Abeta.
   
 0.999
PPP2R1A
Protein phosphatase 2, regulatory subunit A, alpha.
   
 0.999
PPP2CA
PPP2CB isoform 8.
   
 0.990
PPP2CB
Serine/threonine-protein phosphatase.
   
 0.977
ENSPTRP00000029492
annotation not available
   
 0.955
BCL2
BCL2 apoptosis regulator.
    
 0.941
PPP2R5D
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
  
0.928
RYR2
RYR2 isoform 1.
     
 0.927
BUB1B
BUB1B-PAK6 isoform 4.
    
 0.916
PPP1R1A
Protein phosphatase 1 regulatory inhibitor subunit 1A.
     
 0.906
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.