| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DIS3L2 | HEATR1 | ENSPTRP00000042229 | ENSPTRP00000003615 | DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...] | HEAT repeat containing 1. | 0.401 |
| DIS3L2 | MTREX | ENSPTRP00000042229 | ENSPTRP00000028912 | DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...] | Superkiller viralicidic activity 2-like 2. | 0.890 |
| DIS3L2 | PDCD11 | ENSPTRP00000042229 | ENSPTRP00000005127 | DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...] | Programmed cell death 11. | 0.536 |
| DIS3L2 | RRP12 | ENSPTRP00000042229 | ENSPTRP00000078616 | DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...] | Ribosomal RNA processing 12 homolog. | 0.449 |
| DIS3L2 | TARBP1 | ENSPTRP00000042229 | ENSPTRP00000003591 | DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...] | TARBP1 isoform 1. | 0.744 |
| DIS3L2 | TBL3 | ENSPTRP00000042229 | ENSPTRP00000053800 | DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...] | Transducin (Beta)-like 3. | 0.558 |
| DIS3L2 | UTP20 | ENSPTRP00000042229 | ENSPTRP00000083654 | DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...] | UTP20, small subunit (SSU) processome component, homolog. | 0.634 |
| DIS3L2 | UTP4 | ENSPTRP00000042229 | ENSPTRP00000014129 | DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...] | UTP4 small subunit processome component. | 0.551 |
| DIS3L2 | WDR36 | ENSPTRP00000042229 | ENSPTRP00000029316 | DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...] | WD repeat domain 36. | 0.617 |
| HEATR1 | DIS3L2 | ENSPTRP00000003615 | ENSPTRP00000042229 | HEAT repeat containing 1. | DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...] | 0.401 |
| HEATR1 | MTREX | ENSPTRP00000003615 | ENSPTRP00000028912 | HEAT repeat containing 1. | Superkiller viralicidic activity 2-like 2. | 0.956 |
| HEATR1 | PDCD11 | ENSPTRP00000003615 | ENSPTRP00000005127 | HEAT repeat containing 1. | Programmed cell death 11. | 0.993 |
| HEATR1 | POLR1A | ENSPTRP00000003615 | ENSPTRP00000020836 | HEAT repeat containing 1. | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.963 |
| HEATR1 | RRP12 | ENSPTRP00000003615 | ENSPTRP00000078616 | HEAT repeat containing 1. | Ribosomal RNA processing 12 homolog. | 0.971 |
| HEATR1 | TARBP1 | ENSPTRP00000003615 | ENSPTRP00000003591 | HEAT repeat containing 1. | TARBP1 isoform 1. | 0.795 |
| HEATR1 | TBL3 | ENSPTRP00000003615 | ENSPTRP00000053800 | HEAT repeat containing 1. | Transducin (Beta)-like 3. | 0.998 |
| HEATR1 | UTP20 | ENSPTRP00000003615 | ENSPTRP00000083654 | HEAT repeat containing 1. | UTP20, small subunit (SSU) processome component, homolog. | 0.999 |
| HEATR1 | UTP4 | ENSPTRP00000003615 | ENSPTRP00000014129 | HEAT repeat containing 1. | UTP4 small subunit processome component. | 0.998 |
| HEATR1 | WDR36 | ENSPTRP00000003615 | ENSPTRP00000029316 | HEAT repeat containing 1. | WD repeat domain 36. | 0.996 |
| MTREX | DIS3L2 | ENSPTRP00000028912 | ENSPTRP00000042229 | Superkiller viralicidic activity 2-like 2. | DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...] | 0.890 |
