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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALOX5ALOX5 isoform 2. (785 aa)    
Predicted Functional Partners:
ALOX15
Arachidonate 15-lipoxygenase.
  
  
0.945
ALOX12B
ALOX12B isoform 1.
  
 
0.939
ALOX15B
Arachidonate 15-lipoxygenase, type B.
  
 
0.937
PLA2G4A
Phospholipase A2.
   
 
 0.929
PLA2G4F
Phospholipase A2.
     
 0.929
PLA2G4E
Phospholipase A2.
     
 0.928
PLA2G4D
Phospholipase A2.
     
 0.928
LOC749464
Phospholipase A2.
     
 0.928
PLA2G12B
Phospholipase A2 group XIIB.
   
 0.927
LTA4H
Leukotriene A(4) hydrolase; Belongs to the peptidase M1 family.
     
 0.919
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.