| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CCAR2 | SIRT1 | ENSPTRP00000034364 | ENSPTRP00000004394 | Cell cycle and apoptosis regulator 2. | SIRT1 isoform 2. | 0.994 |
| CCAR2 | TP53 | ENSPTRP00000034364 | ENSPTRP00000014836 | Cell cycle and apoptosis regulator 2. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.442 |
| FOXO1 | FOXO3 | ENSPTRP00000009886 | ENSPTRP00000049754 | FOXO1 isoform 1. | FOXO3 isoform 1. | 0.962 |
| FOXO1 | PPARG | ENSPTRP00000009886 | ENSPTRP00000076701 | FOXO1 isoform 1. | Peroxisome proliferator-activated receptor gamma isoform X2. | 0.615 |
| FOXO1 | PPARGC1A | ENSPTRP00000009886 | ENSPTRP00000027470 | FOXO1 isoform 1. | PPARG coactivator 1 alpha. | 0.985 |
| FOXO1 | SIRT1 | ENSPTRP00000009886 | ENSPTRP00000004394 | FOXO1 isoform 1. | SIRT1 isoform 2. | 0.991 |
| FOXO1 | SIRT2 | ENSPTRP00000009886 | ENSPTRP00000018763 | FOXO1 isoform 1. | NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. | 0.837 |
| FOXO1 | SIRT6 | ENSPTRP00000009886 | ENSPTRP00000017501 | FOXO1 isoform 1. | SIRT6 isoform 1. | 0.469 |
| FOXO1 | TP53 | ENSPTRP00000009886 | ENSPTRP00000014836 | FOXO1 isoform 1. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.795 |
| FOXO3 | FOXO1 | ENSPTRP00000049754 | ENSPTRP00000009886 | FOXO3 isoform 1. | FOXO1 isoform 1. | 0.962 |
| FOXO3 | PPARG | ENSPTRP00000049754 | ENSPTRP00000076701 | FOXO3 isoform 1. | Peroxisome proliferator-activated receptor gamma isoform X2. | 0.479 |
| FOXO3 | PPARGC1A | ENSPTRP00000049754 | ENSPTRP00000027470 | FOXO3 isoform 1. | PPARG coactivator 1 alpha. | 0.789 |
| FOXO3 | SIRT1 | ENSPTRP00000049754 | ENSPTRP00000004394 | FOXO3 isoform 1. | SIRT1 isoform 2. | 0.990 |
| FOXO3 | SIRT2 | ENSPTRP00000049754 | ENSPTRP00000018763 | FOXO3 isoform 1. | NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. | 0.760 |
| FOXO3 | SIRT6 | ENSPTRP00000049754 | ENSPTRP00000017501 | FOXO3 isoform 1. | SIRT6 isoform 1. | 0.540 |
| FOXO3 | SIRT7 | ENSPTRP00000049754 | ENSPTRP00000016642 | FOXO3 isoform 1. | SIRT7 isoform 2. | 0.432 |
| FOXO3 | TP53 | ENSPTRP00000049754 | ENSPTRP00000014836 | FOXO3 isoform 1. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.915 |
| PPARG | FOXO1 | ENSPTRP00000076701 | ENSPTRP00000009886 | Peroxisome proliferator-activated receptor gamma isoform X2. | FOXO1 isoform 1. | 0.615 |
| PPARG | FOXO3 | ENSPTRP00000076701 | ENSPTRP00000049754 | Peroxisome proliferator-activated receptor gamma isoform X2. | FOXO3 isoform 1. | 0.479 |
| PPARG | PPARGC1A | ENSPTRP00000076701 | ENSPTRP00000027470 | Peroxisome proliferator-activated receptor gamma isoform X2. | PPARG coactivator 1 alpha. | 0.984 |
