node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALDH18A1 | ALDH4A1 | ENSPTRP00000083069 | ENSPTRP00000000455 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.991 |
ALDH18A1 | CPS1 | ENSPTRP00000083069 | ENSPTRP00000087073 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Carbamoyl-phosphate synthase 1, mitochondrial. | 0.803 |
ALDH18A1 | GLS | ENSPTRP00000083069 | ENSPTRP00000021790 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | GLS isoform 1. | 0.973 |
ALDH18A1 | GLS2 | ENSPTRP00000083069 | ENSPTRP00000008680 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | GLS2 isoform 4. | 0.973 |
ALDH18A1 | GLUD1 | ENSPTRP00000083069 | ENSPTRP00000004734 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Glutamate dehydrogenase 2, mitochondrial; Important for recycling the chief excitatory neurotransmitter, glutamate, during neurotransmission; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.981 |
ALDH18A1 | GLUL | ENSPTRP00000083069 | ENSPTRP00000002925 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Glutamine synthetase. | 0.913 |
ALDH18A1 | PC | ENSPTRP00000083069 | ENSPTRP00000045149 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.622 |
ALDH4A1 | ALDH18A1 | ENSPTRP00000000455 | ENSPTRP00000083069 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.991 |
ALDH4A1 | GLS | ENSPTRP00000000455 | ENSPTRP00000021790 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. | GLS isoform 1. | 0.917 |
ALDH4A1 | GLS2 | ENSPTRP00000000455 | ENSPTRP00000008680 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. | GLS2 isoform 4. | 0.932 |
ALDH4A1 | GLUD1 | ENSPTRP00000000455 | ENSPTRP00000004734 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Glutamate dehydrogenase 2, mitochondrial; Important for recycling the chief excitatory neurotransmitter, glutamate, during neurotransmission; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.940 |
ALDH4A1 | GLUL | ENSPTRP00000000455 | ENSPTRP00000002925 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Glutamine synthetase. | 0.926 |
ALDH4A1 | GOT1 | ENSPTRP00000000455 | ENSPTRP00000004968 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...] | 0.945 |
ALDH4A1 | GOT2 | ENSPTRP00000000455 | ENSPTRP00000013976 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Aspartate aminotransferase. | 0.942 |
CPS1 | ALDH18A1 | ENSPTRP00000087073 | ENSPTRP00000083069 | Carbamoyl-phosphate synthase 1, mitochondrial. | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.803 |
CPS1 | GLS | ENSPTRP00000087073 | ENSPTRP00000021790 | Carbamoyl-phosphate synthase 1, mitochondrial. | GLS isoform 1. | 0.905 |
CPS1 | GLS2 | ENSPTRP00000087073 | ENSPTRP00000008680 | Carbamoyl-phosphate synthase 1, mitochondrial. | GLS2 isoform 4. | 0.910 |
CPS1 | GLUD1 | ENSPTRP00000087073 | ENSPTRP00000004734 | Carbamoyl-phosphate synthase 1, mitochondrial. | Glutamate dehydrogenase 2, mitochondrial; Important for recycling the chief excitatory neurotransmitter, glutamate, during neurotransmission; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.941 |
CPS1 | GLUL | ENSPTRP00000087073 | ENSPTRP00000002925 | Carbamoyl-phosphate synthase 1, mitochondrial. | Glutamine synthetase. | 0.960 |
GLS | ALDH18A1 | ENSPTRP00000021790 | ENSPTRP00000083069 | GLS isoform 1. | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.973 |