STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RBP4Retinol-binding protein 4; Retinol-binding protein that mediates retinol transport in blood plasma. Delivers retinol from the liver stores to the peripheral tissues. Transfers the bound all-trans retinol to STRA6, that then facilitates retinol transport across the cell membrane. (201 aa)    
Predicted Functional Partners:
TTR
Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain (By similarity). Belongs to the transthyretin family.
   
 0.997
STRA6
Stimulated by retinoic acid 6.
     
 0.975
RBP1
Retinol binding protein 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
   
 
 0.803
CRP
Pentaxin.
   
  
 0.631
ALB
ALB isoform 2.
   
 
 0.624
ADIPOQ
Adiponectin, C1Q and collagen domain containing.
   
  
 0.606
AHSG
Alpha-2-HS-glycoprotein chain A; Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions (By similarity); Belongs to the fetuin family.
   
  
 0.599
SLC2A4
SLC2A4 isoform 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
   
  
 0.586
APCS
Pentaxin.
      
 0.581
RETN
RETN isoform 1.
      
 0.578
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.