STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EMX2Empty spiracles homeobox 2. (252 aa)    
Predicted Functional Partners:
SP8
Sp8 transcription factor.
    
 
 0.651
PAX2
PAX2 isoform 1.
      
 0.637
TBR1
T-box brain transcription factor 1.
    
 0.605
FGF8
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
      
 0.603
FOXG1
FOXG1 isoform 8.
   
 0.599
NHLH1
Nescient helix-loop-helix 1.
   
  
 0.583
NEUROG2
NEUROG2 isoform 1.
   
  
 0.577
SIM1
Single-minded homolog 1; Transcriptional factor that may have pleiotropic effects during embryogenesis and in the adult.
      
 0.576
NR4A2
Nuclear receptor subfamily 4, group A, member 2.
      
 0.559
GPRC5D
G protein-coupled receptor class C group 5 member D.
      
 0.548
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.