STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TACC2Transforming acidic coiled-coil containing protein 2. (1094 aa)    
Predicted Functional Partners:
CKAP5
Cytoskeleton associated protein 5.
    
 
 0.890
TRIOBP
TRIOBP isoform 1.
      
 0.886
ZNF780B
ZNF780B isoform 3.
   
 0.824
UBTF
Upstream binding transcription factor, RNA polymerase I.
   
 
 0.812
RMND5B
Required for meiotic nuclear division 5 homolog B.
      
 0.799
PC
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
     
 0.779
TMCO1
Transmembrane and coiled-coil domains 1.
      
 0.742
TACC1
Transforming, acidic coiled-coil containing protein 1.
    
 
0.728
ENSPTRP00000078378
annotation not available
 
  
 
0.728
AURKC
AURKC isoform 1; Belongs to the protein kinase superfamily.
   
 0.600
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.