STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MMP21Matrix metallopeptidase 21. (569 aa)    
Predicted Functional Partners:
TIMP2
CEP295NL isoform 1.
   
 0.678
CDK13
Cyclin dependent kinase 13.
   
  
 0.669
FURIN
Furin (Paired basic amino acid cleaving enzyme); Belongs to the peptidase S8 family.
    
 0.622
LOC469457
CDK11B isoform 2.
      
 0.578
HPX
Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
      
 0.557
TIMP3
TIMP metallopeptidase inhibitor 3.
   
 0.538
ENSPTRP00000071316
annotation not available
   
 0.538
TIMP1
TIMP metallopeptidase inhibitor 1.
   
 0.485
ENSPTRP00000088770
annotation not available
   
 0.485
NID1
NID1 isoform 2.
     
 0.468
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.