CYP2E1 protein (Pan troglodytes) - STRING interaction network

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Score

CYP2E1

Cytochrome P450 family 2 subfamily E member 1; Belongs to the cytochrome P450 family. (531 aa)

Predicted Functional Partners:

CYP3A4

0.979

CYP1A2

0.972

ADH1B

0.969

GSTP1

0.960

GSTM1

0.955

EPHX1

0.955

UGT2B7

0.950

ADH6

0.949

ADH1A

0.949

NAT2

0.949

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADH1A	ADH1B	ENSPTRP00000028008	ENSPTRP00000071388	Alcohol dehydrogenase 1A (class I), alpha polypeptide.	All-trans-retinol dehydrogenase [NAD(+)] ADH1B; Catalyzes the NAD-dependent oxidation of all-trans-retinol and its derivatives such as all-trans-4-hydroxyretinol and may participate to retinoid metabolism. In vitro can also catalyzes the NADH-dependent reduction of all-trans-retinal and its derivatives such as all-trans-4-oxoretinal. Catalyzes in the oxidative direction with higher efficiency. Has the same affinity for all-trans-4-hydroxyretinol and all-trans-4-oxoretinal.	0.973
ADH1A	ADH6	ENSPTRP00000028008	ENSPTRP00000028007	Alcohol dehydrogenase 1A (class I), alpha polypeptide.	Alcohol dehydrogenase 6 (class V).	0.450
ADH1A	CYP2E1	ENSPTRP00000028008	ENSPTRP00000005465	Alcohol dehydrogenase 1A (class I), alpha polypeptide.	Cytochrome P450 family 2 subfamily E member 1; Belongs to the cytochrome P450 family.	0.949
ADH1A	GSTM1	ENSPTRP00000028008	ENSPTRP00000001835	Alcohol dehydrogenase 1A (class I), alpha polypeptide.	GSTM1 isoform 3; Belongs to the GST superfamily.	0.693
ADH1A	GSTP1	ENSPTRP00000028008	ENSPTRP00000047877	Alcohol dehydrogenase 1A (class I), alpha polypeptide.	Glutathione S-transferase pi 1; Belongs to the GST superfamily.	0.792
ADH1A	UGT2B7	ENSPTRP00000028008	ENSPTRP00000063599	Alcohol dehydrogenase 1A (class I), alpha polypeptide.	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	0.658
ADH1B	ADH1A	ENSPTRP00000071388	ENSPTRP00000028008	All-trans-retinol dehydrogenase [NAD(+)] ADH1B; Catalyzes the NAD-dependent oxidation of all-trans-retinol and its derivatives such as all-trans-4-hydroxyretinol and may participate to retinoid metabolism. In vitro can also catalyzes the NADH-dependent reduction of all-trans-retinal and its derivatives such as all-trans-4-oxoretinal. Catalyzes in the oxidative direction with higher efficiency. Has the same affinity for all-trans-4-hydroxyretinol and all-trans-4-oxoretinal.	Alcohol dehydrogenase 1A (class I), alpha polypeptide.	0.973
ADH1B	ADH6	ENSPTRP00000071388	ENSPTRP00000028007	All-trans-retinol dehydrogenase [NAD(+)] ADH1B; Catalyzes the NAD-dependent oxidation of all-trans-retinol and its derivatives such as all-trans-4-hydroxyretinol and may participate to retinoid metabolism. In vitro can also catalyzes the NADH-dependent reduction of all-trans-retinal and its derivatives such as all-trans-4-oxoretinal. Catalyzes in the oxidative direction with higher efficiency. Has the same affinity for all-trans-4-hydroxyretinol and all-trans-4-oxoretinal.	Alcohol dehydrogenase 6 (class V).	0.466
ADH1B	CYP2E1	ENSPTRP00000071388	ENSPTRP00000005465	All-trans-retinol dehydrogenase [NAD(+)] ADH1B; Catalyzes the NAD-dependent oxidation of all-trans-retinol and its derivatives such as all-trans-4-hydroxyretinol and may participate to retinoid metabolism. In vitro can also catalyzes the NADH-dependent reduction of all-trans-retinal and its derivatives such as all-trans-4-oxoretinal. Catalyzes in the oxidative direction with higher efficiency. Has the same affinity for all-trans-4-hydroxyretinol and all-trans-4-oxoretinal.	Cytochrome P450 family 2 subfamily E member 1; Belongs to the cytochrome P450 family.	0.969
ADH1B	GSTM1	ENSPTRP00000071388	ENSPTRP00000001835	All-trans-retinol dehydrogenase [NAD(+)] ADH1B; Catalyzes the NAD-dependent oxidation of all-trans-retinol and its derivatives such as all-trans-4-hydroxyretinol and may participate to retinoid metabolism. In vitro can also catalyzes the NADH-dependent reduction of all-trans-retinal and its derivatives such as all-trans-4-oxoretinal. Catalyzes in the oxidative direction with higher efficiency. Has the same affinity for all-trans-4-hydroxyretinol and all-trans-4-oxoretinal.	GSTM1 isoform 3; Belongs to the GST superfamily.	0.717
ADH1B	GSTP1	ENSPTRP00000071388	ENSPTRP00000047877	All-trans-retinol dehydrogenase [NAD(+)] ADH1B; Catalyzes the NAD-dependent oxidation of all-trans-retinol and its derivatives such as all-trans-4-hydroxyretinol and may participate to retinoid metabolism. In vitro can also catalyzes the NADH-dependent reduction of all-trans-retinal and its derivatives such as all-trans-4-oxoretinal. Catalyzes in the oxidative direction with higher efficiency. Has the same affinity for all-trans-4-hydroxyretinol and all-trans-4-oxoretinal.	Glutathione S-transferase pi 1; Belongs to the GST superfamily.	0.726
ADH1B	UGT2B7	ENSPTRP00000071388	ENSPTRP00000063599	All-trans-retinol dehydrogenase [NAD(+)] ADH1B; Catalyzes the NAD-dependent oxidation of all-trans-retinol and its derivatives such as all-trans-4-hydroxyretinol and may participate to retinoid metabolism. In vitro can also catalyzes the NADH-dependent reduction of all-trans-retinal and its derivatives such as all-trans-4-oxoretinal. Catalyzes in the oxidative direction with higher efficiency. Has the same affinity for all-trans-4-hydroxyretinol and all-trans-4-oxoretinal.	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	0.679
ADH6	ADH1A	ENSPTRP00000028007	ENSPTRP00000028008	Alcohol dehydrogenase 6 (class V).	Alcohol dehydrogenase 1A (class I), alpha polypeptide.	0.450
ADH6	ADH1B	ENSPTRP00000028007	ENSPTRP00000071388	Alcohol dehydrogenase 6 (class V).	All-trans-retinol dehydrogenase [NAD(+)] ADH1B; Catalyzes the NAD-dependent oxidation of all-trans-retinol and its derivatives such as all-trans-4-hydroxyretinol and may participate to retinoid metabolism. In vitro can also catalyzes the NADH-dependent reduction of all-trans-retinal and its derivatives such as all-trans-4-oxoretinal. Catalyzes in the oxidative direction with higher efficiency. Has the same affinity for all-trans-4-hydroxyretinol and all-trans-4-oxoretinal.	0.466
ADH6	CYP2E1	ENSPTRP00000028007	ENSPTRP00000005465	Alcohol dehydrogenase 6 (class V).	Cytochrome P450 family 2 subfamily E member 1; Belongs to the cytochrome P450 family.	0.949
ADH6	GSTM1	ENSPTRP00000028007	ENSPTRP00000001835	Alcohol dehydrogenase 6 (class V).	GSTM1 isoform 3; Belongs to the GST superfamily.	0.680
ADH6	GSTP1	ENSPTRP00000028007	ENSPTRP00000047877	Alcohol dehydrogenase 6 (class V).	Glutathione S-transferase pi 1; Belongs to the GST superfamily.	0.694
ADH6	UGT2B7	ENSPTRP00000028007	ENSPTRP00000063599	Alcohol dehydrogenase 6 (class V).	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	0.666
CYP1A2	CYP2E1	ENSPTRP00000070670	ENSPTRP00000005465	Cytochrome P450 family 1 subfamily A member 2; Belongs to the cytochrome P450 family.	Cytochrome P450 family 2 subfamily E member 1; Belongs to the cytochrome P450 family.	0.972
CYP1A2	CYP3A4	ENSPTRP00000070670	ENSPTRP00000081767	Cytochrome P450 family 1 subfamily A member 2; Belongs to the cytochrome P450 family.	Cytochrome P450 family 3 subfamily A member 4.	0.957